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MHC Class II HLA-DP/DQ/DR 抗体

GMP Grade HLA-DP/DQ/DR 适用: 人 FACS 宿主: 小鼠 Monoclonal IVA12 unconjugated
产品编号 ABIN5067814
发货至: 中国
  • 抗原 See all MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR) products
    MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR)
    适用
    • 18
    • 1
    宿主
    • 16
    • 2
    小鼠
    克隆类型
    • 18
    单克隆
    标记
    • 10
    • 4
    • 2
    • 2
    This MHC Class II HLA-DP/DQ/DR antibody is un-conjugated
    应用范围
    • 16
    • 8
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    原理
    Anti-HLA-DR,DP,DQ Unconjugated Antibody
    产品特性
    The clone IVA12 recognizes the shared epitopes of human leucocyte antigen (HLA) class II molecules HLA-DP, HLA-DQ and HLA-DR heterodimeric cell surface glycoproteins comprised of an α (heavy) chain and a β (light) chain. They are expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional antigen presenting cells (APCs). HLA-Class II expressing APCs specifically present antigens recognized by TCR/CD3 complex of CD4+ T cells. Reactive microglia and perivascular cells in multiple sclerosis lesions express all three types of HLA-Class II molecules, whereas microglia in the normal CNS expressed HLA-DR only.
    纯化方法
    Purified
    纯度
    >95 %
    质量等级
    GMP Grade
    免疫原
    Priess human B cell line
    克隆位点
    IVA12
    亚型
    IgG1, kappa
  • 应用备注
    Each lot of this antibody has been pre-titrated and tested by flow cytometric analysis of human PBMCs such that 0.5µg is sufficient for staining 1 million cells in a 100µl staining volume or 100µl of whole blood. It is recommended to titrate antibody reactivity empirically for optimal performance.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • 抗原
    MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR)
    别名
    HLA-DR, DP, DQ (HLA-DP/DQ/DR 产品)
    途径
    Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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