FNIP1 抗体 (HRP)
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- 抗原 See all FNIP1 抗体
- FNIP1 (Folliculin Interacting Protein 1 (FNIP1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FNIP1 antibody is conjugated to HRP
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- Strong expression is found in the heart, liver placenta, muscle, nasal mucosa, salivary gland and uvula and moderate expression in kidney and lung. Higher levels detected in clear cell renal cell carcinoma (RCC) and chromophobe RCC than in normal kidney tissue.,Detects ~130 kDa.
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Peptide Affinity Purified
- 免疫原
- Synthetic peptide from the mid-protein of Human FNIP1
- 亚型
- IgG
- Top Product
- Discover our top product FNIP1 Primary Antibody
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- 应用备注
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- WB (1:1000)
- ICC/IF (1:100)
- IHC (1:50)
- optimal dilutions for assays should be determined by the user.
- 说明
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A 1:1000 dilution of ABIN5066852 was sufficient for detection of FNIP1 in 15 μg of mouse kidney cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Conjugated antibodies should be stored at 4°C
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- 抗原
- FNIP1 (Folliculin Interacting Protein 1 (FNIP1))
- 别名
- FNIP1 (FNIP1 产品)
- 别名
- FNIP1 antibody, DKFZp468P0310 antibody, A730024A03Rik antibody, AI838773 antibody, AW557298 antibody, folliculin interacting protein 1 antibody, FNIP1 antibody, fnip1 antibody, Fnip1 antibody
- 背景
- Folliculin-interacting protein 1 (FNIP1) is a co-chaperone of HSP90 (1). It Inhibits the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. It may be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways and may regulate the phosphorylation of RPS6KB1 (2). FNIP1 is strongly expressed in the heart, liver placenta, muscle, nasal mucosa, salivary gland, and uvula. Elevated levels of FNIP1 have been detected in renal cell carcinoma (RCC) (3).
- 基因ID
- 96459
- NCBI登录号
- NP_001008738
- UniProt
- Q8TF40
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