beta Arrestin 1 抗体 (AA 150-318)
-
- 抗原 See all beta Arrestin 1 (ARRB1) 抗体
- beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))
-
抗原表位
- AA 150-318
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This beta Arrestin 1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 纯化方法
- Protein A Chromatography
- 免疫原
- A partial length recombinant Beta-arrestin 1 protein (amino acids 150-318) was used as the immunogen for this antibody.
- 亚型
- IgG
- Top Product
- Discover our top product ARRB1 Primary Antibody
-
-
- 应用备注
- WB: 2-4 μg/mL
- 限制
- 仅限研究用
-
- 浓度
- 0.5 mg/mL
- 缓冲液
- PBS containing 0.05 % BSA, PH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
-
- 抗原
- beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))
- 别名
- Beta-arrestin 1 (ARRB1 产品)
- 别名
- arrb1 antibody, MGC83787 antibody, arb1 antibody, arr1 antibody, barr1 antibody, betaarr1 antibody, 1200006I17Rik antibody, AW208571 antibody, G430100A01Rik antibody, ARB1 antibody, ARR1 antibody, BARRES antibody, arrestin beta 1 antibody, arrestin, beta 1 antibody, arrestin beta 1 L homeolog antibody, beta-arrestin 1 antibody, putative beta-arrestin 1 antibody, ARRB1 antibody, arrb1 antibody, arrb1.L antibody, CpipJ_CPIJ016988 antibody, CpipJ_CPIJ017114 antibody, Smp_122900 antibody, Smp_126080 antibody, Smp_176980 antibody, Smp_152290 antibody, Arrb1 antibody
- 背景
- Beta-arrestin 1, a member of arrestin family, is a cofactor of beta-adrenergic receptor kinase (BARK) in beta-adrenergic receptor desensitization and resensitization process. Beta-arrestin 1 acts as endocytic adapter for internalization of many G-protein coupled receptors. Beta-arrestin 1 is also associated with many other cellular processes like ubiquitination and down-regulation of the insulin-like growth factor-1 receptor, synaptic transmission in photoreceptor cells, working as a scaffold protein in G-protein coupled receptor signaling pathways. Two isoforms of beta-arrestin 1 have been identified, isoform 1 (47 kDa) and isoform 2 (46 kDa). Beta-arrestin 1 is highly expressed in liver, kidney, lungs and testes.
- 分子量
- 47 kDa
- 基因ID
- 408
- UniProt
- P49407
- 途径
- Positive Regulation of Peptide Hormone Secretion, Nuclear Hormone Receptor Binding, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
-