WASF1 抗体 (AA 481-559) (AbBy Fluor® 680)
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- 抗原 See all WASF1 抗体
- WASF1 (WAS Protein Family, Member 1 (WASF1))
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抗原表位
- AA 481-559
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This WASF1 antibody is conjugated to AbBy Fluor® 680
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人
- 预测反应
- Mouse,Rat,Dog,Cow,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human WAVE 1
- 亚型
- IgG
- Top Product
- Discover our top product WASF1 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- WASF1 (WAS Protein Family, Member 1 (WASF1))
- 别名
- WAVE 1 (WASF1 产品)
- 别名
- scar1 antibody, wave1 antibody, ATRANGAP2 antibody, ATSCAR1 antibody, SCAR1 antibody, T14G11.27 antibody, T14G11_27 antibody, WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY VERPROLIN HOMOLOGOUS PROTEIN 1 antibody, wave antibody, WAVE antibody, WAVE1 antibody, AI195380 antibody, AI838537 antibody, Scar antibody, WAVE-1 antibody, WAS protein family member 1 S homeolog antibody, SCAR family protein antibody, WAS protein family member 1 antibody, WAS protein family, member 1 antibody, wasf1.S antibody, AT2G34150 antibody, wasf1 antibody, WASF1 antibody, Wasf1 antibody
- 背景
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Synonyms: Protein WAVE-1, Protein WAVE1, SCAR1, Similar to a plant extensin like protein, Verprolin homology domain containing protein 1, Verprolin homology domain-containing protein 1, WAS protein family, member 1, Wasf1, WASF1_HUMAN, WASL, WASP family 1, WASP family protein member 1, WAVE, WAVE1, Wiskott Aldrich syndrome protein family member 1, Wiskott-Aldrich syndrome protein family member 1.
Background: WASP (for Wiskott-Aldrich syndrome protein) and N-WASP are downstream effectors of Cdc42 that are implicated in Actin polymerization and cytoskeletal organization. The WASP family also includes VASP (vasodilator-stimulated phosphoprotein) and Mena (for mammalian enabled protein), which accumulate at focal adhesions and are also involved in the regulation of the Actin cytoskeleton. The WAVE proteins are related to the WASP family proteins and are likewise involved in mediating Actin reorganization downstream of the Rho family of small GTPases. The protein homologs WAVE1 and WAVE2 regulate membrane ruffling by inducing the formation of Actin filament clusters in response to GTP binding and by activating Rac. They mediate Actin polymerization by cooperating with the Arp2/3 complex, thereby promoting the formation of Actin filaments. WAVE1, which is also designated SCAR (suppressor of cAR), is expressed primarily in the brain, while WAVE2 is widely expressed, with the expression highest in peripheral blood leukocytes. WAVE3 forms a multiprotein complex that links receptor kinases with Actin and plays a role in the transduction of signals involving changes in cell shape, function or motility.
- 基因ID
- 8936
- 途径
- RTK signaling, Regulation of Actin Filament Polymerization
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