TOR1B 抗体 (AA 281-336) (AbBy Fluor® 750)
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- 抗原 See all TOR1B 抗体
- TOR1B (Torsin Family 1, Member B (Torsin B) (TOR1B))
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抗原表位
- AA 281-336
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TOR1B antibody is conjugated to AbBy Fluor® 750
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 小鼠
- 预测反应
- Human,Rat,Dog,Cow,Sheep,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Torsin B
- 亚型
- IgG
- Top Product
- Discover our top product TOR1B Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- TOR1B (Torsin Family 1, Member B (Torsin B) (TOR1B))
- 别名
- Torsin B (TOR1B 产品)
- 别名
- MGC82811 antibody, tor1a antibody, 2610016F05Rik antibody, DQ1 antibody, torsinB antibody, torsin family 1, member B (torsin B) L homeolog antibody, torsin family 1, member B (torsin B) antibody, torsin family 1 member B antibody, torsin family 1, member B antibody, tor1b.L antibody, tor1b antibody, TOR1B antibody, Tor1b antibody
- 背景
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Synonyms: DQ1, Tor1b, Torsin 1B, TOR1B, FKSG18, Torsin family 1 member B, TOR1B_HUMAN.
Background: TorsinB is a 336 amino acid protein that localizes to the lumen of endoplasmic reticulum and belongs to the Torsin family. Expressed in a variety of tissues with particularly high levels in adult brain, TorsinB is thought to function as a molecular chaperone that assists in the conformational folding of membrane and secreted proteins. Via its ability to regulate protein folding, TorsinB plays a key role in postnatal developmental events and is essential for proper neurological development. TorsinB contains two PKC (protein kinase C) phosphorylations sites, one ATP binding domain and several conserved cysteines and shares 69 % amino acid identity with TorsinA, a related family member. Defects in the gene encoding TorsinB are associated with torsion dystonia, an autosomal dominant neurological disorder that is characterized by debilitating muscle contractions throughout the body.
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