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ZNF536 抗体 (N-Term)

ZNF536 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN501163
发货至: 中国
  • 抗原 See all ZNF536 抗体
    ZNF536 (Zinc Finger Protein 536 (ZNF536))
    抗原表位
    • 8
    • 8
    • 6
    • 1
    N-Term
    适用
    人, 小鼠, 大鼠
    宿主
    • 15
    克隆类型
    • 15
    多克隆
    标记
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    This ZNF536 antibody is un-conjugated
    应用范围
    • 15
    • 13
    • 13
    • 13
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse, Rat
    纯化方法
    Affinity chromatography
    免疫原
    16 amino acid peptide from near the amino terminus of human ZNF536
    亚型
    IgG
    Top Product
    Discover our top product ZNF536 Primary Antibody
  • 应用备注
    ELISA. Western blot at 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C.
  • 抗原
    ZNF536 (Zinc Finger Protein 536 (ZNF536))
    别名
    ZNF536 (ZNF536 产品)
    别名
    9630010P11Rik antibody, Znf536 antibody, mKIAA0390 antibody, RGD1563363 antibody, zinc finger protein 536 antibody, ZNF536 antibody, Zfp536 antibody
    背景
    ZNF536 is a recently identified zinc-finger protein that is expressed primarily in the developing nervous system and the cerebral cortex, hippocampus, and hypothalamus. ZNF536 possess ten zinc fingers and interacts with CtBP1, a corepressor for gene transcription. It is most closely related to transcriptional repressor ZNF219. Overexpression of ZNF536 in embryonic stem cells dramatically reduced the mRNA levels of neuronal marker genes such as Pax6, MAP2, and b-tubulin III following retinoic acid (RA)-induced differentiation, while depletion of ZNF536 via RNAi resulted in elevated mRNA levels of these genes, indicating its role in inhibiting neuronal cell differentiation. Overexpression of RA receptor a rescues the inhibitory role of ZNF536, suggesting that ZNF536 might inhibit RA response element-mediated transcriptional activity.Synonyms: KIAA0390, Zinc finger protein 532, Zinc finger protein 532
    基因ID
    9745
    NCBI登录号
    NP_055532
    途径
    Retinoic Acid Receptor Signaling Pathway
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