UBE2N 抗体 (C-Term)
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- 抗原 See all UBE2N 抗体
- UBE2N (Ubiquitin-Conjugating Enzyme E2N (UBE2N))
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抗原表位
- C-Term
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UBE2N antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects UBE2N / BLU.
- 交叉反应 (详细)
- Species reactivity (tested):Human, mouse, rat
- 纯化方法
- Ion exchange chromatography
- 免疫原
- UBC13 antibody was raised against a peptide corresponding to 15 amino acids near the C- terminus of human UBC13.
- 亚型
- IgG
- Top Product
- Discover our top product UBE2N Primary Antibody
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- 应用备注
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ELISA. Western blot. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- 抗原
- UBE2N (Ubiquitin-Conjugating Enzyme E2N (UBE2N))
- Abstract
- UBE2N 产品
- 别名
- UBC13 antibody, UbcH-ben antibody, UbcH13 antibody, 1500026J17Rik antibody, AL022654 antibody, BB101821 antibody, ube2n antibody, wu:fb11b03 antibody, wu:fc08b06 antibody, zgc:55726 antibody, ubc13 antibody, ubch-ben antibody, UBE2N antibody, ube2nl antibody, zgc:63901 antibody, ubiquitin conjugating enzyme E2 N antibody, ubiquitin-conjugating enzyme E2N antibody, ubiquitin conjugating enzyme E2 N S homeolog antibody, ubiquitin-conjugating enzyme E2Na antibody, ubiquitin-conjugating enzyme E2Nb antibody, UBE2N antibody, Ube2n antibody, ube2n.S antibody, ube2na antibody, LOC100533434 antibody, ube2n antibody, ube2nb antibody
- 背景
- Ubiquitin-conjugating enzyme 13 (Ubc13) was initially discovered in S. cerevisiae as a DNA-damage inducible protein involved in the error-free DNA postreplication repair pathway (1). It has recently been shown to be an important component of the Toll-like receptor and IL-1R signaling pathway (reviewed in 2). Signals from these pathways are relayed by a number of downstream molecules such as MyD88 and tumor necrosis factor receptor associated factor (TRAF6), ultimately activating various kinases and transcription factors (2,3). Ubc13 is part of a dimeric ubiquitin-conjugating enzyme complex also containing UEV1A (ubiquitin-conjugating enzyme E2 variant 1) that together with TRAF6 activates TAK1, a member of the mitogen-activated protein kinase kinase kinase family (4-6). The Ubc13-UEV1A complex also mediates the Lys-63 ubiquitination of TRAF-6, and this ubiquitination is essential for TAK1 activation (5).Synonyms: Bendless-like ubiquitin-conjugating enzyme, UBC13, Ubiquitin carrier protein N, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-protein ligase N
- 基因ID
- 7334
- 途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Positive Regulation of Response to DNA Damage Stimulus, Ubiquitin Proteasome Pathway
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