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Sphingomyelin Synthase 1 抗体 (AA 331-413) (AbBy Fluor® 750)

SGMS1 适用: 小鼠 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 750
产品编号 ABIN5010926
发货至: 中国
  • 抗原 See all Sphingomyelin Synthase 1 (SGMS1) 抗体
    Sphingomyelin Synthase 1 (SGMS1)
    抗原表位
    • 14
    • 8
    • 8
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    AA 331-413
    适用
    • 28
    • 20
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    小鼠
    宿主
    • 42
    克隆类型
    • 42
    多克隆
    标记
    • 15
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Sphingomyelin Synthase 1 antibody is conjugated to AbBy Fluor® 750
    应用范围
    • 38
    • 20
    • 15
    • 12
    • 12
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    小鼠
    预测反应
    Human,Rat,Dog,Cow,Horse,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Sphingomyelin Synthase 1
    亚型
    IgG
    Top Product
    Discover our top product SGMS1 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    Sphingomyelin Synthase 1 (SGMS1)
    别名
    Sphingomyelin Synthase 1 (SGMS1 产品)
    别名
    MGC81436 antibody, TMEM23 antibody, MOB antibody, MOB1 antibody, SMS1 antibody, hmob33 antibody, 9530058O11Rik antibody, AI841905 antibody, C80702 antibody, Mob antibody, Sms1 antibody, Sor1 antibody, Tmem23 antibody, sphingomyelin synthase 1 antibody, sphingomyelin synthase 1 S homeolog antibody, phosphatidylcholine:ceramide cholinephosphotransferase 1 antibody, SGMS1 antibody, sgms1.S antibody, LOC100013212 antibody, Sgms1 antibody
    背景

    Synonyms: MOB, MOB1, SMS1, TMEM23, hmob33, Phosphatidylcholine:ceramide cholinephosphotransferase 1, Medulla oblongata-derived protein, Protein Mob, Sphingomyelin synthase 1, Transmembrane protein 23, SGMS1

    Background: Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types such as HeLa cells. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.

    基因ID
    259230
    UniProt
    Q86VZ5
    途径
    Cellular Response to Molecule of Bacterial Origin
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