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CRLF2 抗体 (Center)

CRLF2 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN501083
发货至: 中国
  • 抗原 See all CRLF2 抗体
    CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
    抗原表位
    • 15
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    适用
    • 36
    • 24
    • 19
    宿主
    • 47
    • 10
    • 3
    克隆类型
    • 50
    • 10
    多克隆
    标记
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CRLF2 antibody is un-conjugated
    应用范围
    • 34
    • 26
    • 26
    • 14
    • 8
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects CRLF2.
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Peptide affinity chromatography
    免疫原
    TSLP Receptor antibody was raised against a 19 amino acid peptide from near the center of human TSLP receptor.
    亚型
    IgG
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    Discover our top product CRLF2 Primary Antibody
  • 应用备注
    ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
    别名
    CRLF2 (CRLF2 产品)
    别名
    CRLF2 antibody, CRL2 antibody, CRLF2Y antibody, TSLPR antibody, CRLM2 antibody, Ly114 antibody, Tpte2 antibody, Tslpr antibody, Crl2 antibody, cytokine receptor like factor 2 antibody, cytokine receptor-like factor 2 antibody, CRLF2 antibody, Crlf2 antibody
    背景
    Thymic stromal lymphopoietin (TSLP) has recently been identified as an important factor capable of driving dendritic cell maturation and activation. It is involved in the positive selection of regulatory T cells, maintenance of peripheral CD4+ T cell homeostasis and the induction of CD4+ T cell-mediated allergic reaction. TSLP is also capable of supporting the growth of fetal liver and adult B cell progenitors and their differentiation to the IgM-positive stage of B cell development. Its receptor TSLP-R will bind TSLP in a low-affinity fashion in transfected cells, co-transfection with IL-7R-alpha cDNA results in high-affinity binding and a functional heteromeric complex. This heteromeric receptor requires stat5 for TSLP-mediated signal transduction and is inhibited by SOCS-1. Despite its predicted molecular weight, TSLP-R often migrates at a higher molecular weight in SDS-PAGE.Synonyms: Cytokine receptor-like 2, Cytokine receptor-like factor 2, IL-XR, ILXR, TSLPR, Thymic stromal lymphopoietin protein receptor
    基因ID
    64109
    UniProt
    Q9HC73
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