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TRIM25 抗体 (C-Term)

TRIM25 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN501044
发货至: 中国
  • 抗原 See all TRIM25 抗体
    TRIM25 (Tripartite Motif Containing 25 (TRIM25))
    抗原表位
    • 15
    • 15
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 89
    • 8
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 83
    • 6
    克隆类型
    • 84
    • 5
    多克隆
    标记
    • 41
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRIM25 antibody is un-conjugated
    应用范围
    • 78
    • 35
    • 27
    • 27
    • 14
    • 13
    • 10
    • 8
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects TRIM25 / RNF147 at C-term.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse
    纯化方法
    Peptide affinity chromatography
    免疫原
    TRIM25 antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human TRIM25.
    亚型
    IgG
    Top Product
    Discover our top product TRIM25 Primary Antibody
  • 应用备注
    ELISA. Western blot: 1 - 2 μg/mL. Immunoflourescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    TRIM25 (Tripartite Motif Containing 25 (TRIM25))
    别名
    TRIM25 / RNF147 (TRIM25 产品)
    别名
    zgc:55773 antibody, MGC130751 antibody, EFP antibody, RNF147 antibody, Z147 antibody, ZNF147 antibody, AA960166 antibody, AL022677 antibody, Zfp147 antibody, Efp antibody, Znf147 antibody, E3 ubiquitin/ISG15 ligase TRIM25 antibody, tripartite motif containing 25 antibody, E3 ubiquitin/ISG15 ligase TRIM25-like L homeolog antibody, microRNA 3614 antibody, tripartite motif-containing 25 antibody, LOC100146440 antibody, trim25 antibody, LOC100490741.L antibody, TRIM25 antibody, MIR3614 antibody, Trim25 antibody
    背景
    TRIM25, also known as estrogen responsive finger protein (EFP) is a member of the RING finger-B box-coiled coil family and is a downstream target of estrogen receptor a. Mice lacking this gene displayed an underdeveloped uterus and reduced estrogen responsiveness demonstrating that this protein is essential for estrogen dependent proliferation. TRIM25 expression is increased in breast carcinoma where it promotes the growth of breast tumor by functioning as an E3 ubiquitin ligase that targets the negative cell cycle checkpoint 14-3-3s. Recent reports have indicated that TRIM25 E3 ubiquitin ligase is essential for the retinoic-acid-inducible gene 1 (RIG-1) signaling pathway to elicit host antiviral innate immunity.Synonyms: EFP, Estrogen-responsive finger protein, RING finger protein 147, Tripartite motif-containing protein 25, ZNF147, Zinc finger protein 147
    基因ID
    7706
    NCBI登录号
    NP_005073
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