ELISA. Western blot: 2 - 4 μg/mL. Immunohistochemistry on paraffin sections. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
缓冲液
PBS containing 0.02 % sodium azide
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
抗原
TOM70 (TOMM70A)
(Translocase of Outer Mitochondrial Membrane 70 (TOMM70A))
MGC68780 antibody, TOMM70A antibody, Tom70 antibody, KIAA0719 antibody, MGC73188 antibody, zgc:73188 antibody, wu:fj58b04 antibody, CG6756 antibody, Dmel\\CG6756 antibody, dtom70 antibody, GB13743 antibody, TOM70 antibody, 2610044B22Rik antibody, D16Ium22 antibody, D16Ium22e antibody, D16Wsu109e antibody, mKIAA0719 antibody, to translocase of outer mitochondrial membrane 70 S homeolog antibody, translocase of outer mitochondrial membrane 70 antibody, translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) antibody, Translocase of outer membrane 70 antibody, mitochondrial import receptor subunit TOM70 antibody, translocase of outer mitochondrial membrane 70 homolog A (yeast) antibody, tomm70.S antibody, TOMM70 antibody, tomm70a antibody, tomm70 antibody, Tom70 antibody, LOC726081 antibody, Tomm70 antibody, Tomm70a antibody
背景
The translocase of outer mitochondrial membrane (TOM) complex is a multisubunit complex involved in the recognition, unfolding, and translocation of preproteins into the mitochondria. TOM70, an important member of the TOM complex, contains a tetratricopeptide repeat domain similar to those found in cytosolic chaperones such as Hsp90 and Hsc70 and provides a docking site for these proteins. This interaction is thought to be a critical first step in the TOM70-dependent mitochondrial import, followed by contact between the preprotein and TOM70. After targeting to TOM70, preproteins are translocated through the outer membrane via the TOM40 import pore complex. The precise mechanism of how preproteins progress from TOM70 to TOM40 to full translocation is still unclear. At least two isoforms of TOM70 are known to exist.Synonyms: KIAA0719, Mitochondrial import receptor subunit TOM70, Mitochondrial precursor proteins import receptor, TOM70, Translocase of outer membrane 70 kDa subunit