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PRK1 /PRK2 (pThr816) 抗体 (AbBy Fluor® 680)

This anti- antibody is a 兔 多克隆 antibody detecting in IF (cc) 和 IF (p). Suitable for 人.
产品编号 ABIN5009164
发货至: 中国

Quick Overview for PRK1 /PRK2 (pThr816) 抗体 (AbBy Fluor® 680) (ABIN5009164)

抗原

PRK1 /PRK2

适用

宿主

  • 14

克隆类型

  • 14
多克隆

标记

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AbBy Fluor® 680

应用范围

  • 12
  • 12
  • 3
  • 3
  • 3
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    pThr816

    预测反应

    Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human PRK1 around the phosphorylation site of Thr774

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    PRK1 /PRK2

    别名

    PRK1 + PRK2

    背景

    Synonyms: Prokineticin-1/Endocrine-gland-derived vascular endothelial growth factor, PROK1, EGVEGF, PK1, EG-VEGF, PRK1.

    Background: Endocrine gland-derived vascular endothelial growth factor (EG-VEGF) induces proliferation, migration, and fenestration in capillary endothelial cells derived from endocrine glands. EG-VEGF possesses an HIF-1 binding site, its expression is induced by hypoxia and restricted to the steroidogenic glands (ovary, testis, adrenal and placenta). Expression of EG-VEGF is often complementary to the expression of VEGF, suggesting that these molecules function in a coordinated manner. EG-VEGF is an example of a class of highly specific mitogens that act to regulate proliferation and differentiation of the vascular endothelium in a tissue-specific manner. It is expressed primarily in one type of tissue and acts selectively on one type of endothelium. EG-VEGF, possibly through binding to a G protein-coupled receptor, results in the activation of MAPK p44/42 and phosphatidylinositol 3-kinase signaling pathways, leading to proliferation, migration and survival of responsive endothelial cells .

    基因ID

    5585
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