PRICKLE1 抗体 (AA 551-650) (AbBy Fluor® 750)
Quick Overview for PRICKLE1 抗体 (AA 551-650) (AbBy Fluor® 750) (ABIN5009159)
抗原
See all PRICKLE1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 551-650
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交叉反应
- 大鼠
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预测反应
- Human,Mouse,Dog,Cow,Sheep,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Prickle
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亚型
- IgG
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anti-Prickle-Like Protein 1 (PRICKLE1) (AA 684-756) antibody
PRICKLE1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8G5 unconjugated
anti-Prickle-Like Protein 1 (PRICKLE1) (AA 684-756) antibodyPRICKLE1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Prickle-Like Protein 1 (PRICKLE1) (C-Term) antibodyPRICKLE1 适用: 人, 大鼠, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- PRICKLE1 (Prickle-Like Protein 1 (PRICKLE1))
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别名
- Prickle
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背景
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Synonyms: FLJ31627, FLJ31937, MGC138902, MGC138903, EPM1B, Prickle 1, Prickle homolog 1 Drosophila, Prickle like protein 1, Prickle-like 1, Prickle1, REST-Interacting LIM Domain Protein, REST/NRSF interacting LIM domain protein 1, RILP, PRIC1_HUMAN.
Background: Prickle1 is an 831 amino acid protein that contains one PET domain and three LIM zinc-binding domains and localizes to the cytoplasm, as well as to the nuclear membrane. Expressed at higher levels in placenta and at lower levels in liver, brain, kidney, lung and pancreas, Prickle1 is thought to function as a nuclear receptor that interacts with NRSF, a silencer protein that binds the DNA sequence element NRSE (neuron-restrictive silencer element). Defects in the gene encoding Prickle1 are associated with autosomal recessive progressive myoclonic epilepsy-1B, which is characterized by quick jerks of the arms, shoulders or legs. The gene encoding Prickle1 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5 % of the human genome.
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基因ID
- 144165
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途径
- WNT signaling, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development, Protein targeting to Nucleus
抗原
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