ARHGEF17 抗体 (Center)
ARHGEF17
适用: 人
WB, IHC (p), EIA
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all ARHGEF17 抗体
- ARHGEF17 (rho Guanine Nucleotide Exchange Factor (GEF) 17 (ARHGEF17))
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抗原表位
- Center
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ARHGEF17 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects ARHGEF17 / TEM4 at center.
- 交叉反应 （详细）
- Species reactivity (tested):Human
- 纯化方法
- Peptide affinity chromatography
- 免疫原
- TEM4 antibody was raised against a 18 amino acid peptide near the center of human TEM4.
- 亚型
- IgG
- Top Product
- Discover our top product ARHGEF17 Primary Antibody
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anti-rho Guanine Nucleotide Exchange Factor (GEF) 17 (ARHGEF17) (C-Term) antibody
ARHGEF17 适用: 人, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- 抗原
- ARHGEF17 (rho Guanine Nucleotide Exchange Factor (GEF) 17 (ARHGEF17))
- 别名
- ARHGEF17 / TEM4 (ARHGEF17 产品)
- 别名
- P164RHOGEF antibody, TEM4 antibody, p164-RhoGEF antibody, 8030463K16 antibody, AI428794 antibody, AW558066 antibody, BC035332 antibody, mKIAA0337 antibody, Rho guanine nucleotide exchange factor 17 antibody, Rho guanine nucleotide exchange factor (GEF) 17 antibody, ARHGEF17 antibody, Arhgef17 antibody
- 背景
- Rho GTPases, which are activated by specific guanine-nucleotide exchange factors (GEFs), play pivotal roles in several cellular functions. TEM4, encoding a protein containing 1510 amino acids, contains a RhoGEF-specific Dbl homology (DH) domain but lacks their typical pleckstrin homology domain. TEM4 is a Rho-specific GEF with novel structural and regulatory properties and predominant expression in the heart. It couples tyrosine kinase signals with the activation of the rho/rac GTPases, thus leading to cell differentiation and/or proliferation. Elevated levels of TEM4, TEM5, TEM6, TEM7 and TEM7R were also raised in breast cancer tissues. TEM4 could also prove to be useful targets therapeutically.Synonyms: 164 kDa Rho-specific guanine-nucleotide exchange factor, KIAA0337, Rho guanine nucleotide exchange factor 17, Tumor endothelial marker 4, p164-RhoGEF, p164RhoGEF
- 基因ID
- 9828
- UniProt
- Q96PE2
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