IL27 Receptor alpha 抗体 (C-Term)
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- 抗原 See all IL27 Receptor alpha (IL27RA) 抗体
- IL27 Receptor alpha (IL27RA) (Interleukin 27 Receptor, alpha (IL27RA))
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抗原表位
- C-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IL27 Receptor alpha antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects TCCR / IL27RA at C-term.
- 交叉反应 (详细)
- Species reactivity (expected):MouseSpecies reactivity (tested):Human
- 纯化方法
- Peptide affinity chromatography
- 免疫原
- TCCR antibody was raised against a synthetic peptide corresponding to amino acids near the carboxy terminus of human TCCR precursor. Remarks: The sequence is identical to that of mouse TCCR.
- 亚型
- IgG
- Top Product
- Discover our top product IL27RA Primary Antibody
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- 应用备注
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ELISA. Western blot: 0.5 to 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- 抗原
- IL27 Receptor alpha (IL27RA) (Interleukin 27 Receptor, alpha (IL27RA))
- 别名
- TCCR / IL27RA (IL27RA 产品)
- 别名
- IL27RA antibody, CRL1 antibody, IL-27RA antibody, IL27R antibody, TCCR antibody, WSX1 antibody, zcytor1 antibody, IL-27R antibody, Tccr antibody, WSX-1 antibody, Wsx1 antibody, interleukin 27 receptor subunit alpha antibody, interleukin-27 receptor subunit alpha antibody, interleukin 27 receptor, alpha antibody, IL27RA antibody, LOC484907 antibody, Il27ra antibody
- 背景
- Upon antigen challenge, T-helper cells differentiate into two functional distinct subsets, Th1 and Th2. Th1 cells produce IL-2, IFN-gamma and lymphotoxin-beta that augment cell mediated immune response while Th2 cells secrete IL-4, IL-5, and IL-10 that enhance humoral immunity. The function of T-helper cells is regulated by cytokines. A novel cytokine receptor was recently identified and cloned (1,2). It is a new member in the type I cytokine receptor family and designated TCCR for T-cell cytokine receptor and WSX-1 (1,2). TCCR deficient mice had impaired Th1 responses to protein antigen challenge, including decreased levels of IFN-gamma and Th1-dependent antibody IgG2a . TCCR is predominately expressed in thymus, spleen, lymph notes and peripheral blood leukocytes.Synonyms: CRL1, IL-27R-alpha, Interleukin-27 receptor subunit alpha, T-cell cytokine receptor type 1, UNQ296/PRO336, WSX-1, WSX1
- 基因ID
- 9466
- NCBI登录号
- NP_004834
- 途径
- Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response
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