电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

ADAM17 抗体 (C-Term)

ADAM17 适用: 人, 大鼠, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500861
发货至: 中国
  • 抗原 See all ADAM17 抗体
    ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
    抗原表位
    • 16
    • 12
    • 8
    • 7
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 102
    • 51
    • 49
    • 3
    • 3
    • 3
    • 1
    人, 大鼠, 小鼠
    宿主
    • 86
    • 14
    • 2
    • 1
    • 1
    克隆类型
    • 79
    • 25
    多克隆
    标记
    • 48
    • 9
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ADAM17 antibody is un-conjugated
    应用范围
    • 77
    • 47
    • 38
    • 15
    • 14
    • 11
    • 10
    • 10
    • 9
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects CD156b / ADAM17 at C-term. 80 to 130 kDa bands can be detected, which may represent mature protein, precursor, and glycosylated CD156b.
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse, Rat.
    纯化方法
    Immunoaffinity Chromatography
    免疫原
    A peptide corresponding to amino acids near the carboxy terminus of Human CD156b / ADAM17
    亚型
    IgG
    Top Product
    Discover our top product ADAM17 Primary Antibody
  • 应用备注
    ELISA. Western blot: 1: 500 to 1: 2000. Immunoflourescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Wang, Wang, Yin, Zhang, Yu, Kong, Yuan, Fang, Liu, Liu, Shi: "Reduced neurotrophic factor level is the early event before the functional neuronal deficiency in high-fat diet induced obese mice." in: Metabolic brain disease, Vol. 32, Issue 1, pp. 247-257, (2018) (PubMed).

  • 抗原
    ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
    别名
    CD156b / ADAM17 (ADAM17 产品)
    别名
    ADAM18 antibody, CD156B antibody, CSVP antibody, NISBD antibody, TACE antibody, CD156b antibody, Tace antibody, adam17 antibody, si:dkey-81b15.2 antibody, adam18 antibody, cd156b antibody, csvp antibody, tace antibody, fc20b01 antibody, wu:fc20b01 antibody, zgc:63886 antibody, ADAM metallopeptidase domain 17 antibody, a disintegrin and metallopeptidase domain 17 antibody, ADAM metallopeptidase domain 17b antibody, ADAM metallopeptidase domain 17 L homeolog antibody, ADAM metallopeptidase domain 17a antibody, ADAM17 antibody, Adam17 antibody, adam17b antibody, adam17.L antibody, adam17a antibody
    背景
    Tumor-necrosis factor-a is a proinflammatory cytokine and contributes to a variety of inflammatory disease responses and programmed cell death. TNF-alpha is synthesized as a 26K type II membrane-bound precursor that is cleaved by a convertase to generate secreted 17K mature TNF-alpha. TNF-alpha converting enzyme (TACE) protein was recently purified and the human and mouse TACE cDNAs were cloned by several groups separately. TACE is a membrane-bound metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease). TACE also processes other cell surface proteins, including TNF receptor, TGFa, the L-selectin adhesion molecule, and alpha-cleavage of amyloid protein precursor (APP) (4,5). TACE mRNA is expressed in a variety of human and murine tissues. TACE was selected as one of the few targets in cytokine activation by the Eighth International Conference of the Inflammation Research Association.Synonyms: CSVP, Disintegrin and metalloproteinase domain-containing protein 17, Snake venom-like protease, TACE, TNF-alpha convertase, TNF-alpha-converting enzyme
    基因ID
    6868
    NCBI登录号
    NP_003174
    途径
    Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus
You are here:
客服