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SYPL2 抗体 (C-Term)

SYPL2 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500857
发货至: 中国
  • 抗原 See all SYPL2 抗体
    SYPL2 (Synaptophysin-Like 2 (SYPL2))
    抗原表位
    C-Term
    适用
    人, 小鼠, 大鼠
    宿主
    • 1
    克隆类型
    • 1
    多克隆
    标记
    • 1
    This SYPL2 antibody is un-conjugated
    应用范围
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects SYPL2. It will not cross-react with SYPL1.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat
    纯化方法
    Peptide affinity chromatography
    免疫原
    SYPL2 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human SYPL.
    亚型
    IgG
  • 应用备注
    ELISA. Western blot. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    SYPL2 (Synaptophysin-Like 2 (SYPL2))
    别名
    SYPL2 (SYPL2 产品)
    别名
    AI552439 antibody, Mg29 antibody, MG29 antibody, mg29 antibody, MGC88982 antibody, Sypl antibody, fc22a07 antibody, wu:fc22a07 antibody, zgc:110355 antibody, sypl antibody, wu:fd54d09 antibody, zgc:65838 antibody, synaptophysin-like 2 antibody, synaptophysin like 2 antibody, synaptophysin like 2 S homeolog antibody, synaptophysin-like 2b antibody, synaptophysin-like 2a antibody, Sypl2 antibody, SYPL2 antibody, sypl2.S antibody, sypl2 antibody, sypl2b antibody, sypl2a antibody
    背景
    SYPL2, also known as Mitsugumin 29, was initially identified as a transmembrane protein from the triad junction in skeletal muscle that had significant homology with members of the synaptophysin family. SYPL2 is thought to participate in the excitation-contraction coupling process of skeletal muscle as SYPL2-null mice showed reduced muscle contractile force and altered triad junction structure and increased susceptibility to fatigue of the skeletal muscle. SYPL2 plays a critical role in muscle Ca2+ signaling by regulating the process of store-operated Ca2+ entry and interacts with ryanodine receptor (RyR), thereby influencing intracellular Ca2+ homeostasis through changes in the RyR/Ca2+ release function. Co-expression of SYPL2 and RyR in cultured cells leads to apoptotic cell death resulting from the depletion of Ca2+ from the intracellular stores. At least two isoforms of SYPL2 are known to exist.Synonyms: Synaptophysin-like protein 2
    基因ID
    284612
    NCBI登录号
    NP_001035799
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