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Paralemmin 抗体 (AA 130-230) (AbBy Fluor® 750)

PALM 适用: 小鼠 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 750
产品编号 ABIN5008346
发货至: 中国
  • 抗原 See all Paralemmin (PALM) 抗体
    Paralemmin (PALM)
    抗原表位
    • 14
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 130-230
    适用
    • 18
    • 14
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 24
    • 4
    克隆类型
    • 25
    • 3
    多克隆
    标记
    • 11
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Paralemmin antibody is conjugated to AbBy Fluor® 750
    应用范围
    • 24
    • 13
    • 12
    • 12
    • 4
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    小鼠
    预测反应
    Human,Rat,Dog,Cow,Sheep,Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Paralemmin 1
    亚型
    IgG
    Top Product
    Discover our top product PALM Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    Paralemmin (PALM)
    别名
    Paralemmin 1 (PALM 产品)
    别名
    PALM antibody, palm antibody, zgc:110136 antibody, paralemmin antibody, paralemmin 1a antibody, paralemmin S homeolog antibody, PALM antibody, palm1a antibody, palm antibody, palm.S antibody, Palm antibody
    背景

    Synonyms: KIAA0270, PALM, PALM_HUMAN, Paralemmin, Paralemmin1,Paralemmin-1.

    Background: Paralemmin, also called Paralemmin-1 or PALM, is a widely expressed peripheral membrane protein that is involved in cell structure and shape. A hydrophobic protein, Paralemmin is anchored to the cytoplasmic side of the cell membrane via di-palmitoylation and prenylation of its C-terminal cysteine cluster. Functioning at the synapse to regulate neuronal plasticity and plasma membrane dynamics, Paralemmin can bind to the dopamine receptor D3, thereby reducing D3 expression and subsequent adenylate cyclase activity. Overexpression of Paralemmin induces fibroblasts to extend long filopodia and to assume extreme cell shapes, suggesting involvement in the formation and stabilization of the plasma membrane. Two isoforms of Paralemmin exists due to alternative splicing events.

    途径
    cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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