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- 抗原 See all ST3GAL6 抗体
- ST3GAL6 (ST3 beta-Galactoside alpha-2,3-Sialyltransferase 6 (ST3GAL6))
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抗原表位
- C-Term
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ST3GAL6 antibody is un-conjugated
- 应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA), Immunofluorescence (IF)
- 特异性
- This antibody detects ST3GAL6.
- 交叉反应 （详细）
- Species reactivity (tested):Human, Mouse and Rat
- 纯化方法
- Peptide Affinity Chromatography
- 免疫原
- ST3gal6 antibody was raised against a 16 amino acid peptide from near the carboxy terminus of Human ST3gal6.
- 亚型
- IgG
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- 应用备注
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ELISA. Western blot: 1 - 2 μg/mL. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- ST3GAL6 (ST3 beta-Galactoside alpha-2,3-Sialyltransferase 6 (ST3GAL6))
- 别名
- ST3GAL6 (ST3GAL6 产品)
- 别名
- SIAT10 antibody, ST3GALVI antibody, 1700023B24Rik antibody, AI930218 antibody, AW552396 antibody, Siat10 antibody, St3galVI antibody, ST3GAL-VI antibody, ST3 beta-galactoside alpha-2,3-sialyltransferase 6 antibody, ST3GAL6 antibody, St3gal6 antibody
- 背景
- Sialyltransferases catalyze the transfer of sialic acid from cytidine 5-prime monophospho-N-acetylneuraminic acid (CMP-NeuAc) to terminal positions of glycoprotein and glycolipid carbohydrate groups. Terminal NeuAc residues are key determinants of carbohydrate structures, such as the sialyl-Lewis X determinants, and are widely distributed in many cell types. However, cancer cells often express more heavily sialylated glycans on their cell surface and this feature sometimes correlates with invasiveness. In contrast, expression of ST3gal6, a member of the sialyltransferase family that sialylates type II lactosamine structures on glycoproteins and glycolipids, was found to be significantly decreased by hypermethylation of the gene in gastrointestinal cancer. At least three isoforms of ST3gal6 are known to exist.Synonyms: 3-sialyltransferase, 3-sialyltransferase VI, CMP-NeuAc:beta-galactoside alpha-2, SIAT10, ST3Gal VI, ST3GalVI, Sialyltransferase 10, Type 2 lactosamine alpha-2
- 基因ID
- 10402
- NCBI登录号
- NP_006091
- 途径
- Glycosaminoglycan Metabolic Process
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