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SPRED1 抗体 (Center)

SPRED1 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500796
发货至: 中国
  • 抗原 See all SPRED1 抗体
    SPRED1 (Sprouty-Related, EVH1 Domain Containing 1 (SPRED1))
    抗原表位
    • 7
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    适用
    人, 小鼠, 大鼠
    宿主
    • 37
    • 7
    克隆类型
    • 37
    • 7
    多克隆
    标记
    • 20
    • 6
    • 5
    • 5
    • 4
    • 4
    This SPRED1 antibody is un-conjugated
    应用范围
    • 39
    • 34
    • 20
    • 7
    • 6
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects SPRED1 at center. It is predicted to have no cross-reactivity to Spred2 or Spred3.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat
    纯化方法
    Peptide affinity chromatography
    免疫原
    Spred1 antibody was raised against a 20 amino acid peptide near the center of the human Spred1.
    亚型
    IgG
    Top Product
    Discover our top product SPRED1 Primary Antibody
  • 应用备注
    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    SPRED1 (Sprouty-Related, EVH1 Domain Containing 1 (SPRED1))
    别名
    SPRED1 (SPRED1 产品)
    别名
    fb14c08 antibody, fj51c03 antibody, zgc:85707 antibody, wu:fb14c08 antibody, wu:fj51c03 antibody, Xspred1 antibody, Xtspred1 antibody, 5730461F13Rik antibody, AL024345 antibody, AW047647 antibody, NFLS antibody, hSpred1 antibody, spred-1 antibody, sprouty-related, EVH1 domain containing 1 antibody, sprouty related EVH1 domain containing 1 antibody, sprouty related, EVH1 domain containing 1 antibody, sprouty related, EVH1 domain containing 1 L homeolog antibody, SPRED1 antibody, sprouty protein with EVH-1 domain 1, related sequence antibody, spred1 antibody, SPRED1 antibody, spred1.L antibody, Bm1_51610 antibody, Spred1 antibody
    背景
    The Ras-MAP kinase pathway is essential for the differentiation of neuronal cells and myocytes, it is inhibited by Spred1, a member of the Sprouty family of proteins. Spred1 acts by suppressing the phosphorylation and activation of Raf. The Spred proteins have also been implicated in the negative feedback regulation of FGF signaling in embryogenesis and angiogenesis. Further studies have shown that expression levels of Spred1 and Spred2 proteins are inversely correlated with the incidence of tumor invasion and metastasis in human hepatocellular carcinoma (HHC), suggesting that these proteins could be useful as prognostic factors and therapeutic targets in HCC. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS).Synonyms: EVH1/Sprouty domain containing protein, NFLS, Spred-1, Suppressor of Ras/MAPK activation
    基因ID
    161742
    NCBI登录号
    NP_689807
    途径
    Positive Regulation of Response to DNA Damage Stimulus
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