PLEKHG6 抗体 (AA 451-550) (AbBy Fluor® 750)
-
- 抗原 See all PLEKHG6 抗体
- PLEKHG6 (Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 6 (PLEKHG6))
-
抗原表位
- AA 451-550
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This PLEKHG6 antibody is conjugated to AbBy Fluor® 750
-
应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Dog,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human MyoGEF
- 亚型
- IgG
- Top Product
- Discover our top product PLEKHG6 Primary Antibody
-
-
- 应用备注
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
-
- 抗原
- PLEKHG6 (Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 6 (PLEKHG6))
- 别名
- MyoGEF (PLEKHG6 产品)
- 别名
- MyoGEF antibody, BC026778 antibody, Gm155 antibody, pleckstrin homology and RhoGEF domain containing G6 antibody, pleckstrin homology domain containing, family G (with RhoGef domain) member 6 antibody, PLEKHG6 antibody, Plekhg6 antibody
- 背景
-
Synonyms: Myosin interacting guanine nucleotide exchange factor, PH domain containing family G member 6, Pleckstrin homology domain containing family G with RhoGef domain member 6, Pleckstrin homology domain-containing family G member 6, PLEKHG6_PKHG6_HUMAN
Background: MyoGEF functions as a guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. It activates RHOG but not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving MyoGEF, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis.
- 基因ID
- 55200
-