MMP17 抗体 (AA 101-200) (AbBy Fluor® 750)
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- 抗原 See all MMP17 抗体
- MMP17 (Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17))
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抗原表位
- AA 101-200
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MMP17 antibody is conjugated to AbBy Fluor® 750
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 小鼠
- 预测反应
- Human,Rat
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human MMP17
- 亚型
- IgG
- Top Product
- Discover our top product MMP17 Primary Antibody
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anti-Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17) antibody
MMP17 适用: 人 WB, IHC (p), ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17) (AA 432-460), (C-Term) antibodyMMP17 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB33781 unconjugated
anti-Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17) (Cleaved-Gln129) antibodyMMP17 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17) antibodyMMP17 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17) antibodyMMP17 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17) (cleaved), (Gln129) antibodyMMP17 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17) (AA 391-420) antibodyMMP17 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB2033-2034 unconjugated
anti-Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17) (Middle Region) antibodyMMP17 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- MMP17 (Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17))
- 别名
- MMP-17 (MMP17 产品)
- 别名
- MT4-MMP antibody, CBTF antibody, DRBF antibody, DRBP76 antibody, MMP4 antibody, MPHOSPH4 antibody, MPP4 antibody, NF-AT-90 antibody, NF110 antibody, NF110b antibody, NF90 antibody, NF90a antibody, NF90b antibody, NFAR antibody, NFAR-1 antibody, NFAR2 antibody, TCP110 antibody, TCP80 antibody, MT4MMP antibody, MTMMP4 antibody, mmp17 antibody, matrix metallopeptidase 17 antibody, interleukin enhancer binding factor 3 antibody, matrix metallopeptidase 17a antibody, MMP17 antibody, ILF3 antibody, Mmp17 antibody, mmp17a antibody
- 背景
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Synonyms: Matrix metalloproteinase-17, MMP-17, MMP17, MTMMP 4, Matrix metalloproteinase 17, Matrix metalloproteinase 17 membrane inserted, Membrane type 4 matrix metalloproteinase, Membrane type matrix metalloproteinase 4, MMP 17, MT MMP 4, MT MMP4, MT4 MMP, MT4MMP.
Background: The matrix metalloproteinases (MMPs) are a family of at least eighteen secreted and membrane bound zincendopeptidases. Collectively, these enzymes can degrade all the components of the extracellular matrix, including fibrillar and non fibrillar collagens, fibronectin, laminin and basement membrane glycoproteins. In general, a signal peptide, a propeptide, and a catalytic domain containing the highly conserved zinc binding site characterizes the structure of the MMPs. In addition, fibronectin like repeats, a hinge region, and a C terminal hemopexin like domain allow categorization of MMPs into the collagenase, gelatinase, stomelysin and membrane type MMP subfamilies. All MMPs are synthesized as proenzymes, and most of them are secreted from the cells as proenzymes. Thus, the activation of these proenzymes is a critical step that leads to extracellular matrix breakdown. MMPs are considered to play an important role in wound healing, apoptosis, bone elongation, embryo development, uterine involution, angiogenesis and tissue remodeling, and in diseases such as multiple sclerosis, Alzheimer's, malignant gliomas, lupus, arthritis, periodontis, glumerulonephritis, atherosclerosis, tissue ulceration, and in cancer cell invasion and metastasis.MMP17 has been reported to be elevated in several tumor cell lines, and is constituitively produced by some normal cell lines. Treatment of cells with Concanavolin A or the phorbol ester TPA stimulates production of MMP17 in some cell types, and the enzyme can be recovered in cell lysates. Shed forms of MMP17 have also been reported.
- 基因ID
- 4326
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