SCO1 抗体 (Center)
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- 抗原 See all SCO1 抗体
- SCO1 (SCO1 Cytochrome C Oxidase Assembly Protein (SCO1))
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抗原表位
- Center
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SCO1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects SCO1 / SCOD1 (both isoforms). It has no cross-reactivity to SCO2.
- 交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
- 纯化方法
- Peptide affinity chromatography
- 免疫原
- SCO1 antibody was raised against a 14 amino acid peptide from near the center of human SCO1.
- 亚型
- IgG
- Top Product
- Discover our top product SCO1 Primary Antibody
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anti-SCO1 Cytochrome C Oxidase Assembly Protein (SCO1) (AA 1-301) antibody
SCO1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-SCO1 Cytochrome C Oxidase Assembly Protein (SCO1) (AA 1-160) antibodySCO1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SCO1 Cytochrome C Oxidase Assembly Protein (SCO1) (AA 125-158) antibodySCO1 适用: 人 WB 宿主: 兔 Polyclonal RB48404 unconjugated
anti-SCO1 Cytochrome C Oxidase Assembly Protein (SCO1) (AA 29-176) antibodySCO1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SCO1 Cytochrome C Oxidase Assembly Protein (SCO1) (AA 202-301) antibodySCO1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-SCO1 Cytochrome C Oxidase Assembly Protein (SCO1) (AA 107-156) antibodySCO1 适用: 人, 小鼠, 大鼠, Cow, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- 抗原
- SCO1 (SCO1 Cytochrome C Oxidase Assembly Protein (SCO1))
- 别名
- SCO1 / SCOD1 (SCO1 产品)
- 背景
- Synthesis of cytochrome c oxidase 1 was initially identified in yeast as one of two cytochrome c oxidase (COX) assembly proteins that enable the assembly of cytochrome c holoenzyme, a complex that catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons across the inner mitochondrial membrane. Like their yeast homologs, the function of both SCO1 and SCO2 are dependent on copper ion binding. Mutations in either gene can lead to cytochrome c oxidase respiratory chain defects, with a missense mutation in human SCO1 (P174L) associated with a fatal neonatal hepatopathy when the second allele is also non-functional, suggesting the pathology is due to loss of function. It has been suggested that this mutation alters the SCO1 affinity for the copper (I) ion, thus impairing the efficiency of copper transfer to the cytochrome c oxidase. At least two isoforms of SCO1 are known to exist.Synonyms: Protein SCO1 homolog mitochondrial
- 基因ID
- 6341
- UniProt
- O75880
- 途径
- Sensory Perception of Sound, Transition Metal Ion Homeostasis, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity
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