MARCH9 抗体 (AbBy Fluor® 680)
-
- 抗原 See all MARCH9 抗体
- MARCH9 (Membrane-Associated Ring Finger (C3HC4) 9 (MARCH9))
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This MARCH9 antibody is conjugated to AbBy Fluor® 680
-
应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human MARCH9
- 亚型
- IgG
- Top Product
- Discover our top product MARCH9 Primary Antibody
-
-
- 应用备注
- IF(IHC-P) 1:50-200
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
-
- 抗原
- MARCH9 (Membrane-Associated Ring Finger (C3HC4) 9 (MARCH9))
- 别名
- MARCH9 (MARCH9 产品)
- 别名
- Rnf179 antibody, March-IX antibody, MARCH-IX antibody, RNF179 antibody, AI608492 antibody, BC019560 antibody, membrane associated ring-CH-type finger 9 antibody, membrane associated ring-CH-type finger 9 S homeolog antibody, membrane-associated ring finger (C3HC4) 9 antibody, March9 antibody, march9.S antibody, MARCH9 antibody, march9 antibody
- 背景
-
Synonyms: E3 ubiquitin protein ligase MARCH9, MARCH IX, Membrane associated RING CH protein IX, membrane associated ring finger C3HC4 9, Membrane associated RING finger protein 9, RING finger protein 179, RNF179, MARH9_HUMAN.
Background: Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). MARCH9 (membrane-associated ring finger (C3HC4) 9), also known as RNF179, is a 346 amino acid multi-pass membrane protein that localizes to the golgi apparatus and contains one RING-CH-type zinc finger. Expressed ubiquitously, MARCH9 exists as a homodimer and functions as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and is thought to promote the degradation of target proteins, such as CD4 and MHC-I. Multiple isoforms of MARCH9 exist due to alternative splicing events.
- 基因ID
- 92979
-