DLGAP3 抗体 (C-Term)
DLGAP3
适用: 人, 小鼠, 大鼠
WB, IHC (p), EIA
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all DLGAP3 抗体
- DLGAP3 (Discs, Large (Drosophila) Homolog-Associated Protein 3 (DLGAP3))
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抗原表位
- C-Term
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DLGAP3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects SAPAP3.
- 交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
- 纯化方法
- Peptide affinity chromatography
- 免疫原
- SAPAP3 antibody was raised against a 18 amino acid peptide from near the carboxy terminus of human SAPAP3.
- 亚型
- IgG
- Top Product
- Discover our top product DLGAP3 Primary Antibody
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anti-Discs, Large (Drosophila) Homolog-Associated Protein 3 (DLGAP3) (AA 1-100) antibody
DLGAP3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- 抗原
- DLGAP3 (Discs, Large (Drosophila) Homolog-Associated Protein 3 (DLGAP3))
- 别名
- DLGAP3 (DLGAP3 产品)
- 别名
- DAP3 antibody, SAPAP3 antibody, BC058433 antibody, DAP-3 antibody, Prpl8 antibody, Sapap3 antibody, Dap3 antibody, DLG associated protein 3 antibody, discs, large (Drosophila) homolog-associated protein 3 antibody, DLGAP3 antibody, Dlgap3 antibody, dlgap3 antibody
- 背景
- SAP90/PSD-95-associated protein 3 (SAPAP3, also known as DLGAP3) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP3 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). Both SAPAP3 protein and mRNA are targeted to dendrites, whereas SAPAP1, -2, and -4 mRNAs are detected mainly in cell bodies. Recent experiments have suggested that SAPAP3 may be involved in obsessive-compulsive disorder (OCD), as mice lacking SAPAP3 exhibited OCD-like symptoms which could be relieved by lentiviral-mediated selective expression of SAPAP3 in the striatum of SAPAP3-mutant mice. At least two isoforms are known to exist.Synonyms: DAP-3, DAP3, Disks large-associated protein 3, PSD-95/SAP90-binding protein 3, SAP90/PSD-95-associated protein 3, SAPAP3
- 基因ID
- 58512
- UniProt
- O95886
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