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RSPO1 抗体 (N-Term)

RSPO1 适用: 人, 大鼠, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500638
发货至: 中国
  • 抗原 See all RSPO1 抗体
    RSPO1 (R-Spondin 1 (RSPO1))
    抗原表位
    • 15
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    N-Term
    适用
    • 43
    • 38
    • 33
    • 15
    • 15
    • 15
    • 15
    • 15
    人, 大鼠, 小鼠
    宿主
    • 46
    • 6
    • 1
    克隆类型
    • 47
    • 6
    多克隆
    标记
    • 22
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This RSPO1 antibody is un-conjugated
    应用范围
    • 36
    • 15
    • 13
    • 11
    • 10
    • 8
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects RSPO1. It will not cross-react with RSPO family members.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat
    纯化方法
    Peptide affinity chromatography
    免疫原
    RSPO1 antibody was raised against a 16 amino acid peptide from near the amino terminus of human RSPO1.
    亚型
    IgG
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    Discover our top product RSPO1 Primary Antibody
  • 应用备注
    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    RSPO1 (R-Spondin 1 (RSPO1))
    别名
    RSPO1 (RSPO1 产品)
    别名
    RGD1565558 antibody, CRISTIN3 antibody, RSPO antibody, R-spondin antibody, Rspondin antibody, wu:fj81e05 antibody, zgc:92153 antibody, R-spondin 1 antibody, Rspo1 antibody, RSPO1 antibody, LOC100049655 antibody, rspo1 antibody
    背景
    RSPO1 is a member of a family of secreted growth factors that can operate through the canonical Wnt signaling pathway by stabilizing the intracellular b-catenin, thereby regulating functions mediated by b-catenin such as cell fate decisions and embryonic patterning. RSPO1 was recently identified through linkage analysis to be involved in sex determination and mammalian ovarian development. RSPO1 is thought to regulate cellular responsiveness to Wnt ligands by modulating the cell-surface expression of the Wnt co-receptor LRP6 by interfering with the DKK/Kremen-mediated internalization of LRP6 through an interaction with Kremen, resulting in increased LRP6 cell-surface levels. At least two isoforms of RSPO1 are known to exist.Synonyms: R-spondin-1, Roof plate-specific spondin-1
    基因ID
    284654
    NCBI登录号
    NP_001033722
    UniProt
    Q2MKA7
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