LGI4 抗体 (AA 101-200) (AbBy Fluor® 750)
-
- 抗原 See all LGI4 抗体
- LGI4 (Leucine-Rich Repeat LGI Family, Member 4 (LGI4))
-
抗原表位
- AA 101-200
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This LGI4 antibody is conjugated to AbBy Fluor® 750
-
应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human LGI4
- 亚型
- IgG
- Top Product
- Discover our top product LGI4 Primary Antibody
-
-
- 应用备注
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
-
- 抗原
- LGI4 (Leucine-Rich Repeat LGI Family, Member 4 (LGI4))
- 别名
- LGI4 (LGI4 产品)
- 别名
- Lgil3 antibody, clp antibody, LGIL3 antibody, leucine rich repeat LGI family member 4 antibody, leucine-rich repeat LGI family, member 4 antibody, LGI4 antibody, Lgi4 antibody
- 背景
-
Synonyms: Leucine rich glioma inactivated gene 4, Leucine rich glioma inactivated protein 4, leucine-rich repeat LGI family member 4, Leucine rich repeat LGI family member 4, LGI1 like protein 3, LGI4, Lgi4 protein, Lgil3, LGI4_HUMAN.
Background: LGI4, also known as leucine-rich glioma-inactivated protein 4, is a 537 amino acid secreted glycosylated protein that is widely expressed, with highest levels found within the nervous system. Interestingly, siRNA knockdown studies of LGI4 expression in Schwann cells have been shown to result in the inhibition of myelination, thus suggesting that LGI4 is an essential component of myelin formation and axon segregation. LGI4 shares significant homology with its other family members, LGI1, LGI2 and LGI3. Significantly, mutations in the gene encoding LGI1 have been linked to human temporal lobe epilepsy and, given the sequence similarity of LGI4, it is likely that it also may be implicated in the pathology of seizures. LGI4 is localized subcellularly to the Golgi, ER and vesicles. There are two isoforms of LGI4 that are produced as a result of alternative splicing events.
- 基因ID
- 163175
-