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MEX3D 抗体 (Center)

MEX3D 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500616
发货至: 中国
  • 抗原 See all MEX3D 抗体
    MEX3D (Mex-3 Homolog D (MEX3D))
    抗原表位
    • 15
    • 1
    • 1
    Center
    适用
    • 17
    • 15
    • 15
    宿主
    • 16
    • 1
    克隆类型
    • 17
    多克隆
    标记
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This MEX3D antibody is un-conjugated
    应用范围
    • 17
    • 13
    • 13
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects Rkhd1.
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Peptide affinity chromatography
    免疫原
    Rkhd1 antibody was raised against a 15 amino acid peptide from near the center of human Rkhd1.
    亚型
    IgG
    Top Product
    Discover our top product MEX3D Primary Antibody
  • 应用备注
    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    MEX3D (Mex-3 Homolog D (MEX3D))
    别名
    MEX3D / RKHD1 (MEX3D 产品)
    别名
    RKHD1 antibody, MEX3D antibody, rkhd1 antibody, mex3 antibody, tino antibody, rnf193 antibody, ok/sw-cl.4 antibody, MEX-3D antibody, MEX3 antibody, OK/SW-cl.4 antibody, RNF193 antibody, TINO antibody, BC059858 antibody, Rkhd1 antibody, mex-3 RNA binding family member D antibody, mex-3 RNA binding family member D L homeolog antibody, mex3 RNA binding family member D antibody, MEX3D antibody, mex3d.L antibody, mex3d antibody, Mex3d antibody
    背景
    Rkhd1, also known as TINO or MEX3D is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module. MEX3 proteins, including Rkhd1, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway. These proteins are a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms. Rkhd1 binds to the AU-rich element in the 3'-untranslated region of Bcl-2 mRNA and is thought to be a negative regulator of Bcl-2 expression. Rkhd3 and Rkhd4, but not Rkhd1, co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover.Synonyms: KIAA2031, RING finger and KH domain-containing protein 1, RING finger protein 193, RNA-binding protein MEX3D, RNF193, TINO
    基因ID
    399664
    UniProt
    Q86XN8
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