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RIMS3 抗体 (N-Term)

RIMS3 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500610
发货至: 中国
  • 抗原 See all RIMS3 抗体
    RIMS3 (Regulating Synaptic Membrane Exocytosis 3 (RIMS3))
    抗原表位
    • 15
    • 2
    • 1
    • 1
    N-Term
    适用
    • 21
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 21
    克隆类型
    • 21
    多克隆
    标记
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RIMS3 antibody is un-conjugated
    应用范围
    • 20
    • 13
    • 13
    • 7
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects Rim3 at N-term. It is predicted to have no cross-reactivity to other Rim proteins.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse
    纯化方法
    Peptide affinity chromatography
    免疫原
    Rim3 antibody was raised against a 17 amino acid peptide from near the amino terminus of human Rim3.
    亚型
    IgG
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  • 应用备注
    ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    RIMS3 (Regulating Synaptic Membrane Exocytosis 3 (RIMS3))
    别名
    RIMS3 (RIMS3 产品)
    别名
    NIM3 antibody, RIM3 antibody, Nim2 antibody, Nim3 antibody, A730060M23Rik antibody, Rim3 antibody, mKIAA0237 antibody, RIMS3 antibody, MGC145981 antibody, si:ch211-239d6.1 antibody, regulating synaptic membrane exocytosis 3 antibody, RIMS3 antibody, Rims3 antibody, rims3 antibody
    背景
    Rab3-interacting molecules (RIMs) are synaptic proteins are synaptic proteins necessary for neural transmission and plasticity. While both Rim1 and Rim 2 are thought to be effector proteins for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner, less is known of Rim3. Expression of Rim3 in PC12 cells induced a significant increase in calcium-triggered exocytosis, with no appreciable change in the baseline release, suggesting that it plays a role in the regulation of exocytosis. Rim3 protein localizes primarily to neuronal dendrites and the postsynaptic densities, as opposed to Rim1 which is found in presynapse locations, indicating that Rim3 may contribute to synapse transmission and plasticity.Synonyms: KIAA0237, Nim3, RIM 3, RIM3 gamma, Rab-3-interacting molecule 3, Regulating synaptic membrane exocytosis protein 3
    基因ID
    9783
    NCBI登录号
    NP_055562
    UniProt
    Q9UJD0
    途径
    Stem Cell Maintenance, Synaptic Vesicle Exocytosis
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