RHBDD1 抗体 (C-Term)
Quick Overview for RHBDD1 抗体 (C-Term) (ABIN500589)
抗原
See all RHBDD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse
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纯化方法
- Peptide affinity chromatography
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免疫原
- RHBDD1 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human RHBDD1.
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亚型
- IgG
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anti-Rhomboid Domain Containing 1 (RHBDD1) (AA 206-315) antibody
RHBDD1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Rhomboid Domain Containing 1 (RHBDD1) antibodyRHBDD1 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Rhomboid Domain Containing 1 (RHBDD1) (C-Term) antibodyRHBDD1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- RHBDD1 (Rhomboid Domain Containing 1 (RHBDD1))
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别名
- RHBDD1
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背景
- The Rhomboid family of proteins is made up of several widely conserved polytopic membrane serine proteases that play roles in growth and development. RHBDD1 is highly expressed in the testis and is involved in the cleavage of BIK, a proapoptotic member of the Bcl-2 family. Overexpression or suppression by RNAi of RHBDD1 in 293 cells will reduce or enhance BIK-mediated apoptosis, respectively, demonstrating that RHBDD1 modulates BIK-mediated apoptotic activity. In GC-1 cells, a spermatogonia cell line that can differentiate into spermatids within the seminiferous tubules, suppression of RHBDD1 expression by RNAi caused the cells to lose the ability to survive and differentiate in mouse seminiferous tubules, suggesting that RHBDD1 may be associated with mammalian spermatogenesis.Synonyms: HSD-50, HSD50, Rhomboid domain-containing protein 1
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基因ID
- 84236
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UniProt
- Q8TEB9
抗原
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