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RHBDD1 抗体 (C-Term)

RHBDD1 适用: 人, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500589
发货至: 中国
  • 抗原 See all RHBDD1 抗体
    RHBDD1 (Rhomboid Domain Containing 1 (RHBDD1))
    抗原表位
    • 2
    • 1
    C-Term
    适用
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 6
    克隆类型
    • 6
    多克隆
    标记
    • 6
    This RHBDD1 antibody is un-conjugated
    应用范围
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse
    纯化方法
    Peptide affinity chromatography
    免疫原
    RHBDD1 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human RHBDD1.
    亚型
    IgG
    Top Product
    Discover our top product RHBDD1 Primary Antibody
  • 应用备注
    ELISA. Western blot: 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C.
  • 抗原
    RHBDD1 (Rhomboid Domain Containing 1 (RHBDD1))
    别名
    RHBDD1 (RHBDD1 产品)
    别名
    MGC84665 antibody, RRP4 antibody, 4930418P06Rik antibody, mRHBDD1 antibody, RGD1306477 antibody, rRHBDD1 antibody, rhomboid domain containing 1 antibody, rhomboid domain containing 1 L homeolog antibody, RHBDD1 antibody, rhbdd1.L antibody, rhbdd1 antibody, Rhbdd1 antibody
    背景
    The Rhomboid family of proteins is made up of several widely conserved polytopic membrane serine proteases that play roles in growth and development. RHBDD1 is highly expressed in the testis and is involved in the cleavage of BIK, a proapoptotic member of the Bcl-2 family. Overexpression or suppression by RNAi of RHBDD1 in 293 cells will reduce or enhance BIK-mediated apoptosis, respectively, demonstrating that RHBDD1 modulates BIK-mediated apoptotic activity. In GC-1 cells, a spermatogonia cell line that can differentiate into spermatids within the seminiferous tubules, suppression of RHBDD1 expression by RNAi caused the cells to lose the ability to survive and differentiate in mouse seminiferous tubules, suggesting that RHBDD1 may be associated with mammalian spermatogenesis.Synonyms: HSD-50, HSD50, Rhomboid domain-containing protein 1
    基因ID
    84236
    UniProt
    Q8TEB9
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