Junctophilin 3 抗体 (AA 181-280) (AbBy Fluor® 750)
-
- 抗原 See all Junctophilin 3 (JPH3) 抗体
- Junctophilin 3 (JPH3)
-
抗原表位
- AA 181-280
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Junctophilin 3 antibody is conjugated to AbBy Fluor® 750
-
应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Zebrafish
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Junctophilin 3
- 亚型
- IgG
- Top Product
- Discover our top product JPH3 Primary Antibody
-
-
- 应用备注
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
-
- 抗原
- Junctophilin 3 (JPH3)
- 别名
- Junctophilin 3 (JPH3 产品)
- 别名
- CAGL237 antibody, HDL2 antibody, JP-3 antibody, JP3 antibody, TNRC22 antibody, Jp3 antibody, fc26e06 antibody, si:ch211-255l14.9 antibody, wu:fc26e06 antibody, junctophilin 3 antibody, JPH3 antibody, Jph3 antibody, jph3 antibody
- 背景
-
Synonyms: JP-3, JP3, JPH3, JPH3_HUMAN, Junctophilin3, Junctophilin type 3, Junctophilin-3, TNRC22, Trinucleotide repeat-containing gene 22 protein.
Background: Junctophilins are components of the junctional complexes between plasma membranes and endoplasmic or sarcoplasmic reticulums present in all excitable cells. Junctophilins contain a cytoplasmic domain which binds to the plasma membrane, as well as an ER/SR membrane spanning hydrophobic C-terminal segment. The three subtypes in this family are Junctophilin-1, -2 and -3. Junctophilin-1 is predominantly expressed in skeletal muscle, but is also expressed at low levels in heart. Junctophilin-2 is expressed in heart and skeletal muscle. Mutant mice lacking the Jph2 gene exhibit embryonic lethality and possess cardiac myocytes that express abnormal calcium transients. Junctophilin-3 is expressed in brain. The JPH3 alternatively spliced exon 2A has been suggested as a site for CTG repeat expansion leading to a Huntington disease-like autosomal dominant disorder.
-