HSD17B8 抗体 (AA 174-220) (AbBy Fluor® 750)
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- 抗原 See all HSD17B8 抗体
- HSD17B8 (Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8))
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抗原表位
- AA 174-220
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HSD17B8 antibody is conjugated to AbBy Fluor® 750
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 小鼠
- 预测反应
- Human,Rat,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human HSD17B8
- 亚型
- IgG
- Top Product
- Discover our top product HSD17B8 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- HSD17B8 (Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8))
- 别名
- HSD17B8 (HSD17B8 产品)
- 别名
- KE6 antibody, fabgl antibody, zgc:112550 antibody, si:dz12f11.4 antibody, HKE6 antibody, FABGL antibody, ke6 antibody, fabg antibody, hke6 antibody, ring2 antibody, h2-ke6 antibody, d6s2245e antibody, D17H6S112E antibody, H-2Ke6 antibody, Hsd17b8 antibody, Ke-6 antibody, Ke6 antibody, Ring2 antibody, D6S2245E antibody, FABG antibody, H2-KE6 antibody, RING2 antibody, SDR30C1 antibody, dJ1033B10.9 antibody, Fabgl antibody, hydroxysteroid (17-beta) dehydrogenase 8 antibody, hydroxysteroid 17-beta dehydrogenase 8 antibody, H2-K region expressed gene 6 antibody, hsd17b8 antibody, HSD17B8 antibody, H2-Ke6 antibody, Hsd17b8 antibody
- 背景
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Synonyms: 17 beta HSD 8, 17 beta hydroxysteroid dehydrogenase 8, 17-beta-HSD 8, 17-beta-hydroxysteroid dehydrogenase 8, 3-oxoacyl-[acyl-carrier-protein] reductase, Beta ketoacyl [acyl carrier protein] reductase like, D6S2245E, DHB8_HUMAN, dJ1033B10.9, Estradiol 17 beta dehydrogenase 8, Estradiol 17-beta-dehydrogenase 8, Estrogen 17 oxidoreductase, FABG, FABGL, H2 KE6, HKE6, HSD17B8, Hydroxysteroid 17 beta dehydrogenase 8, 17beta hydroxysteroid dehydrogenase type 8, Ke-6, KE6, Protein Ke6, Really interesting new gene 2 protein, RING2, SDR30C1, Short chain dehydrogenase/reductase family 30C member 1, Testosterone 17 beta dehydrogenase 8, Testosterone 17-beta-dehydrogenase 8.
Background: 17beta-HSD8 belongs to the 17beta-HSD family of proteins that regulate the availability of steroids within a tissue. 17beta-HSD8 converts active steroids to their inactive form through its oxidative activity. It is a key player in the inactivation of Estradiol and Testosterone. 17beta-HSD8 is predominantly expressed in placenta, endometrium and prostate but can also be found in liver, and pancreas, with lowest levels found in testis, ovary and kidney. It has been proposed that a reduction in the levels of 17beta-HSD8 may lead to abnormal elevations in the local level of sex steroids, which can lead to recessive renal cystic disease. It has also been suggested that low levels of 17beta-HSD proteins may result in an underdeveloped urogenital system.
- 基因ID
- 7923
- 途径
- Steroid Hormone Biosynthesis
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