PALB2 抗体 (C-Term)
(1 reference)-
- 抗原 See all PALB2 抗体
- PALB2 (Partner and Localizer of BRCA2 (PALB2))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PALB2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects PALB2.
- 交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
- 纯化方法
- Peptide affinity chromatography
- 免疫原
- PALB2 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human PALB2.
- 亚型
- IgG
- Top Product
- Discover our top product PALB2 Primary Antibody
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anti-Partner and Localizer of BRCA2 (PALB2) (AA 1101-1186) antibody
PALB2 适用: 人, Pig WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Partner and Localizer of BRCA2 (PALB2) (AA 677-726) antibodyPALB2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Partner and Localizer of BRCA2 (PALB2) (AA 675-725) antibodyPALB2 适用: 人 WB, IHC, IP, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Partner and Localizer of BRCA2 (PALB2) (AA 99-198) antibodyPALB2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Partner and Localizer of BRCA2 (PALB2) (AA 546-574) antibodyPALB2 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB19074 unconjugated
anti-Partner and Localizer of BRCA2 (PALB2) (AA 553-582), (Middle Region) antibodyPALB2 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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: "Functional variant analyses (FVAs) predict pathogenicity in the BRCA1 DNA double-strand break repair pathway." in: Human molecular genetics, Vol. 24, Issue 11, pp. 3030-7, (2016) (PubMed).
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: "Functional variant analyses (FVAs) predict pathogenicity in the BRCA1 DNA double-strand break repair pathway." in: Human molecular genetics, Vol. 24, Issue 11, pp. 3030-7, (2016) (PubMed).
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- 抗原
- PALB2 (Partner and Localizer of BRCA2 (PALB2))
- 别名
- PALB2 (PALB2 产品)
- 别名
- PALB2 antibody, Fancn antibody, si:ch211-14k19.9 antibody, FANCN antibody, PNCA3 antibody, 4732427B05 antibody, BC066140 antibody, RGD1304759 antibody, partner and localizer of BRCA2 antibody, partner and localizer of BRCA2 L homeolog antibody, PALB2 antibody, palb2 antibody, palb2.L antibody, Palb2 antibody
- 背景
- The breast cancer early onset proteins BRCA1 and BRCA2 are central to the repair of DNA damage by homologous recombination and are strongly associated with inherited breast and ovarian cancer. The protein PALB2 is required for the localization of BRCA2 to sites of DNA damage and like BRCA1 and 2 is a breast cancer susceptibility gene. PALB2 is thought to function through directly binding to BRCA1, which allows the PALB2 protein to organize BRCA2 and the recombinase RAD51 at the site of DNA damage. Analysis of the BRCA1-PALB2-BRCA2-RAD51network may allow predictions to be made of the responsiveness of a particular tumor to therapeutic treatments. At least four isoforms of PALB2 are known to exist.Synonyms: FANCN, Partner and localizer of BRCA2
- 基因ID
- 79728
- UniProt
- Q86YC2
- 途径
- DNA Damage Repair
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