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PAK7 抗体 (Center)

PAK7 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500443
发货至: 中国
  • 抗原 See all PAK7 抗体
    PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))
    抗原表位
    • 8
    • 8
    • 8
    • 7
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    适用
    • 54
    • 17
    • 15
    • 1
    宿主
    • 57
    克隆类型
    • 57
    多克隆
    标记
    • 22
    • 6
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PAK7 antibody is un-conjugated
    应用范围
    • 41
    • 35
    • 32
    • 13
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects PAK5.
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Peptide affinity chromatography
    免疫原
    13 amino acid peptide from near the center of human PAK5
    亚型
    IgG
    Top Product
    Discover our top product PAK7 Primary Antibody
  • 应用备注
    ELISA. Western blot. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))
    别名
    PAK7 / PAK5 (PAK7 产品)
    别名
    PAK5 antibody, pak5 antibody, 2900083L08Rik antibody, 6430627N20 antibody, Pak5 antibody, PAK-5 antibody, PAK-7 antibody, p21 (RAC1) activated kinase 5 antibody, p21 (RAC1) activated kinase 5 L homeolog antibody, p21 protein (Cdc42/Rac)-activated kinase 7 antibody, p21 (RAC1) activated kinase 7 antibody, PAK5 antibody, pak5.L antibody, Pak7 antibody
    背景
    The p21-activated kinases (PAKs) are serine-threonine kinases that bind to the active forms of Cdc42 and Rac. They are divided into two groups, the first of which include PAK1, 2 and 3, and can be activated by Cdc42/Rac binding. Group 1 PAKs contain an autoinhibitory domain whose activity is regulated by Cdc42/Rac binding. The group 1 PAKs are known to be involved in cellular processes such as gene transcription, apoptosis, and cell morphology and motility. Much less is known about the second group, which includes PAK4, 5 and 6. These proteins are not activated by Cdc42/Rac binding. PAK5 was initially identified as a kinase expressed primarily in brain that while possessing a kinase domain and GTPase binding domain similar to PAK4 and PAK6, is completely different from both. Expression of PAK5 in neural based cell lines resulted in neurite outgrowth suggesting that PAK5 may be involved in regulating the cytoskeletal changes necessary for promoting neurite outgrowth. Other experiments suggest that unlike the other PAKs, PAK5 may inhibit apoptosis by phosphorylating the Bcl-2 family member Bad.Synonyms: KIAA1264, PAK-5, PAK-7, Serine/threonine-protein kinase PAK 7, p21-activated kinase 5, p21-activated kinase 7
    基因ID
    57144
    UniProt
    Q9P286
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