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TP53INP1 抗体 (N-Term)

TP53INP1 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500435
发货至: 中国
  • 抗原 See all TP53INP1 抗体
    TP53INP1 (Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1))
    抗原表位
    • 12
    • 9
    • 8
    • 8
    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 54
    • 27
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 61
    克隆类型
    • 52
    • 8
    多克隆
    标记
    • 24
    • 6
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This TP53INP1 antibody is un-conjugated
    应用范围
    • 42
    • 34
    • 31
    • 11
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects TP53INP1.
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse, Rat.
    纯化方法
    Peptide Affinity Chromatography
    免疫原
    A synthetic peptide corresponding to 14 amino acids near the amino terminus of Human p53DINP1. .Remarks: This sequence is identical between apha and beta forms of the p53DINP1 proteins, and differs by one amino acid from those of Mouse.
    亚型
    IgG
    Top Product
    Discover our top product TP53INP1 Primary Antibody
  • 应用备注
    ELISA. Western blot (1-2 μg/mL). Human lung tissue lysate can be used as a Positive Control and a band at 27 kDa can bedetected. A lower band at 18 kDa was detected in Human spleen, and Mouse liver andkidney tissue lysates, which may represent the p53DINP1-beta form. Immunohistochemistry on Paraffin Sections (2 μg/mL).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • Ferrajoli, Ivan, Ciccone, Shimizu, Kita, Ohtsuka, DAbundo, Qiang, Lerner, Nouraee, Rabe, Rassenti, Van Roosbroeck, Manning, Yuan, Zhang, Shanafelt, Wierda, Sabbioni, Tarrand, Estrov, Radovich, Liang et al.: "Epstein-Barr Virus MicroRNAs are Expressed in Patients with Chronic Lymphocytic Leukemia and Correlate with Overall Survival. ..." in: EBioMedicine, Vol. 2, Issue 6, pp. 572-82, (2016) (PubMed).

  • 抗原
    TP53INP1 (Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1))
    别名
    TP53INP1 (TP53INP1 产品)
    别名
    cb1036 antibody, wu:fb70a09 antibody, wu:fi13h08 antibody, zgc:158431 antibody, TP53INP1 antibody, 2700057G22Rik antibody, SIP antibody, SIP18 antibody, SIP27 antibody, Stinp antibody, Teap antibody, TP53DINP1 antibody, TP53INP1A antibody, TP53INP1B antibody, p53DINP1 antibody, Trp53inp1 antibody, tumor protein p53 inducible nuclear protein 1 antibody, tumor protein p53 inducible nuclear protein 1 S homeolog antibody, transformation related protein 53 inducible nuclear protein 1 antibody, TP53INP1 antibody, tp53inp1.S antibody, tp53inp1 antibody, Trp53inp1 antibody, Tp53inp1 antibody
    背景
    Apoptosis is related to many diseases and development. The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes. A novel p53 inducible gene was identified recently and designated p53DINP1 (for p53-dependent damage-inducible nuclear protein 1) and SIP (for stress induced protein) in human and mouse (1,2).?A p53DINP1 antisense oligonucleotide inhibits and overexpression of p53DINP1 enhances Ser46 phosphorylation of p53, induction of p53AIP1, and cell death induced by DNA double-strand breaks (1). p53DINP1 may regulate p53-dependent apoptosis through phosphorylation at Ser46 and induction of p53AIP1. The p53DINP1/SIP gene encodes two proteins of 27 and 18 kDa in human and mouse termed p53DINP1-a and p53DINP1-b or SIP27 and SIP18 (1,2). p53DINP1/SIP is expressed in many tissues and induced by a variety of stress agents including UV stress, mutagenic stress, heat shock, and oxidative stress (2).Synonyms: P53DINP1, SIP, Stress-induced protein, Tumor protein p53-inducible nuclear protein 1, p53-dependent damage-inducible nuclear protein 1, p53-inducible nuclear protein 1
    基因ID
    94241
    UniProt
    Q96A56
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