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ORAI3 抗体 (N-Term)

ORAI3 适用: 人, 大鼠, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500425
发货至: 中国
  • 抗原 See all ORAI3 抗体
    ORAI3 (ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3))
    抗原表位
    • 13
    • 9
    • 9
    • 1
    • 1
    • 1
    N-Term
    适用
    • 25
    • 7
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 22
    • 3
    克隆类型
    • 22
    • 3
    多克隆
    标记
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    This ORAI3 antibody is un-conjugated
    应用范围
    • 25
    • 17
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects ORAI3 at N-term. It is predicted to have no cross-reactivity to ORAI1 or ORAI2.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat
    纯化方法
    Peptide affinity chromatography
    免疫原
    ORAI3 antibody was raised against a 15 amino acid peptide from near the amino terminus of human ORAI3.
    亚型
    IgG
    Top Product
    Discover our top product ORAI3 Primary Antibody
  • 应用备注
    ELISA. Western blot: 1 - 2 μg/mL. Immunoflourescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    ORAI3 (ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3))
    别名
    ORAI3 (ORAI3 产品)
    别名
    ORAI3 antibody, TMEM142C antibody, 9930124N15 antibody, BC061259 antibody, Tmem142c antibody, RGD1306538 antibody, ORAI calcium release-activated calcium modulator 3 antibody, ORAI3 antibody, Orai3 antibody
    背景
    Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI3 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. All three homologs have been shown to function as Ca++ plasma membrane channels gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor. However, ORAI3 channels failed to produce detectable Ca++ selective currents in cells co-transfected with ORAI3 and STIM1, indicating that ORAI3 channels undergo a lesser degree of depotentiation than ORAI1 or ORAI2. Na+ currents through ORAI1, 2 and 3 channels were equally inhibited by extracellular Ca++, indicating that each have similar affinities for Ca++ within the selectivity filter.Synonyms: ORAI-3, TMEM142C, Transmembrane Protein 142C
    基因ID
    93129
    UniProt
    Q9BRQ5
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