GPR37L1 抗体 (AA 101-200) (AbBy Fluor® 680)
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- 抗原 See all GPR37L1 抗体
- GPR37L1 (G Protein-Coupled Receptor 37 Like 1 (GPR37L1))
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抗原表位
- AA 101-200
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GPR37L1 antibody is conjugated to AbBy Fluor® 680
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human GPR37L1
- 亚型
- IgG
- Top Product
- Discover our top product GPR37L1 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- GPR37L1 (G Protein-Coupled Receptor 37 Like 1 (GPR37L1))
- 别名
- GPR37L1 (GPR37L1 产品)
- 别名
- GPR37L1 antibody, ET(B)R-LP-2 antibody, ETBR-LP-2 antibody, AW047233 antibody, CAG-18 antibody, D0Kist8 antibody, G protein-coupled receptor 37 like 1 antibody, G protein-coupled receptor 37-like 1 antibody, GPR37L1 antibody, Gpr37l1 antibody
- 背景
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Synonyms: Endothelin B receptor-like protein 2, ET(B)R-LP-2, ETBR-LP-2, ETBR2, ETBRLP2, G-protein coupled receptor 37-like 1, GPR37L1, ETBR2_HUMAN.
Background: G-protein coupled receptor. Has been shown to bind the neuroprotective and glioprotective factor prosaposin (PSAP), leading to endocytosis followed by an ERK phosphorylation cascade. However, other studies have shown that prosaposin does not increase activity. It has been suggested that GPR37L1 is a constitutively active receptor which signals through the guanine nucleotide-binding protein G(s) subunit alpha. Participates in the regulation of postnatal cerebellar development by modulating the Shh pathway. Regulates baseline blood pressure in females and protects against cardiovascular stress in males. Mediates inhibition of astrocyte glutamate transporters and reduction in neuronal N-methyl-D-aspartate receptor activity.
- 基因ID
- 9283
- UniProt
- O60883
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