Reticulon 4 抗体 (Isoform 1)
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- 抗原 See all Reticulon 4 (RTN4) 抗体
- Reticulon 4 (RTN4)
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抗原表位
- Isoform 1
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Reticulon 4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects RTN4 / NOGO at Center. It is specific for NogoA and NogoE.
- 交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
- 纯化方法
- Peptide affinity chromatography
- 免疫原
- NogoA antibody was raised against a 19 amino acid peptide from near the center of human NogoA.
- 亚型
- IgG
- Top Product
- Discover our top product RTN4 Primary Antibody
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anti-Reticulon 4 (RTN4) (AA 501-515) antibody
RTN4 适用: 人, 猴 IHC, IHC (p) 宿主: 山羊 Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (AA 14-30) antibodyRTN4 适用: 人, 小鼠, 大鼠, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (AA 251-357) antibodyRTN4 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (AA 301-400) antibodyRTN4 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (AA 28-58) antibodyRTN4 适用: 人 WB 宿主: 兔 Polyclonal RB54371 unconjugated
anti-Reticulon 4 (RTN4) (AA 81-130) antibodyRTN4 适用: 人, 小鼠, 大鼠, 兔, 绵羊, Cow, 犬, 猴, 马, 豚鼠, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (AA 254-303) antibodyRTN4 适用: 人, 小鼠, 大鼠, 兔, 绵羊, Cow, 犬, 猴, 马, Pig, Bat, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (AA 166-179) antibodyRTN4 适用: 人, 猴 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (Middle Region) antibodyRTN4 适用: 人, 小鼠, 大鼠, 兔, 绵羊, Cow, 犬, 马, 豚鼠, Pig, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- 抗原
- Reticulon 4 (RTN4)
- 别名
- Reticulon-4 / RTN4 (RTN4 产品)
- 别名
- ASY antibody, NI220/250 antibody, NOGO antibody, NOGO-A antibody, NOGOC antibody, NSP antibody, NSP-CL antibody, Nbla00271 antibody, Nbla10545 antibody, Nogo-B antibody, Nogo-C antibody, RTN-X antibody, RTN4-A antibody, RTN4-B1 antibody, RTN4-B2 antibody, RTN4-C antibody, RTN4-Cw antibody, DKFZp459C0314 antibody, 1110020G17Rik antibody, AA407876 antibody, AA409940 antibody, AA960376 antibody, C130026I10Rik antibody, NgA antibody, Nogo-A antibody, mKIAA0886 antibody, mKIAA4153 antibody, NI-250 antibody, Nogo antibody, Vp20 antibody, r antibody, rat N antibody, rat NogoA antibody, reticulon-4 antibody, nogo antibody, rtn4 antibody, wu:fb17a02 antibody, wu:fb22f12 antibody, wu:fd61a07 antibody, zgc:92163 antibody, reticulon 4 antibody, reticulon 4a antibody, RTN4 antibody, rtn4 antibody, Rtn4 antibody, rtn4a antibody
- 背景
- NogoA is a member of a family of integral membrane proteins termed reticulons that are thought to be involved in numerous disorders including neurodegenerative diseases. Reticulon proteins are known to regulate many cellular processes and interact with multiple proteins and receptors such as BACE. NogoA was initially identified as a myelin-associated neurite outgrowth inhibitor. It is highly expressed in oligodendrocytes in the white matter of the CNS, blocking its activity with antibodies or other factors results in improved axon regrowth and functional recovery in experimental CNS lesion models. NogoA has also been suggested to play a role in neurodegenerative diseases such as Amyotrophic lateral sclerosis, in which case NogoA is found at elevated levels in postmortem muscular samples, and multiple sclerosis (MS), in which case autoantibodies to NogoA have been found in serum and cerebrospinal fluid in MS patients. Despite its predicted molecular weight, NogoA typically migrates at 180 kDa in an SDS-PAGE. At least five isoforms of Nogo are known to exist.Synonyms: Foocen, KIAA0886, NOGO, NSP, Neurite outgrowth inhibitor, Neuroendocrine-specific protein, Neuroendocrine-specific protein C homolog, Reticulon-5
- 基因ID
- 57142
- NCBI登录号
- NP_065393
- UniProt
- Q9NQC3
- 途径
- Neurotrophin Signaling Pathway, Regulation of Cell Size, SARS-CoV-2 Protein Interactome
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