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TACR3 抗体 (Center)

TACR3 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500361
发货至: 中国
  • 抗原 See all TACR3 抗体
    TACR3 (Tachykinin Receptor 3 (TACR3))
    抗原表位
    • 16
    • 14
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    适用
    • 52
    • 26
    • 26
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 53
    克隆类型
    • 53
    多克隆
    标记
    • 22
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TACR3 antibody is un-conjugated
    应用范围
    • 26
    • 22
    • 14
    • 13
    • 13
    • 8
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects Tachykinin receptor 3 (TACR3) at center. It does not recognize NK1R or NK2R.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse
    纯化方法
    Peptide affinity chromatography
    免疫原
    NK3R antibody was raised against a 18 amino acid peptide from near the center of human NK3R.
    亚型
    IgG
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    Discover our top product TACR3 Primary Antibody
  • 应用备注
    ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    TACR3 (Tachykinin Receptor 3 (TACR3))
    Abstract
    TACR3 产品
    别名
    HH11 antibody, NK-3R antibody, NK3R antibody, NKR antibody, TAC3RL antibody, Nk3r antibody, Nkr antibody, Tac3r antibody, Nmkr antibody, tachykinin receptor 3 antibody, neuromedin-K receptor antibody, TACR3 antibody, LOC100544805 antibody, Tacr3 antibody
    背景
    The tachykinins are a family of small peptides that include the neurotransmitters substance P, neurokinin A, and neurokinin B, which can act on three related but distinct seven transmembrane G-proteins coupled receptors, albeit at different concentrations. The NK-3 receptor (NK3R) has greatest affinity for neurokinin B and is highly expressed in the supraoptic and paraventricular nuclei. Following binding of its ligand, NK3R activates a phosphatidylinositol-calcium second messenger system. It is likely these signals lead to the release of vasopressin and oxytocin into the circulation. NK3R may be involved in learning and memory as mice lacking this gene expressed cognitive deficits compared to normal mice. Although it has been suggested that NK3R plays a role in the regulation of vagal afferent relay neurons, it is likely that these receptors are activated by substance P or neurokinin A, as the airway nerves do not express neurokinin B.Synonyms: NK-3 receptor, NK-3R, NK3R, NKR, Neurokinin B receptor, Neuromedin-K receptor, TAC3R
    基因ID
    6870
    NCBI登录号
    NP_001050
    UniProt
    P29371
    途径
    Feeding Behaviour
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