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GLDC 抗体 (AA 51-150) (AbBy Fluor® 750)

GLDC 适用: 人 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 750
产品编号 ABIN5003528
发货至: 中国
  • 抗原 See all GLDC 抗体
    GLDC (Glycine Dehydrogenase (GLDC))
    抗原表位
    • 14
    • 8
    • 8
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-150
    适用
    • 46
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 47
    克隆类型
    • 47
    多克隆
    标记
    • 18
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GLDC antibody is conjugated to AbBy Fluor® 750
    应用范围
    • 43
    • 19
    • 12
    • 12
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    预测反应
    Human,Mouse,Rat,Dog,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human GLDC
    亚型
    IgG
    Top Product
    Discover our top product GLDC Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    GLDC (Glycine Dehydrogenase (GLDC))
    别名
    GLDC (GLDC 产品)
    别名
    PSPTO1276 antibody, Tb07.43M14.350 antibody, DDBDRAFT_0219205 antibody, DDBDRAFT_0231130 antibody, DDB_0219205 antibody, DDB_0231130 antibody, D030049L12Rik antibody, D19Wsu57e antibody, GCE antibody, GCSP antibody, HYGN1 antibody, fb23b05 antibody, wu:fb23b05 antibody, zgc:66198 antibody, gldc antibody, glycine dehydrogenase (decarboxylating) GcvP antibody, glycine dehydrogenase antibody, glycine cleavage system P-protein antibody, glycine decarboxylase antibody, glycine dehydrogenase (decarboxylating) antibody, glycine decarboxylase S homeolog antibody, gcvP antibody, Tb927.7.1910 antibody, Gldc antibody, GLDC antibody, gldc antibody, gldc.S antibody
    背景

    Synonyms: GCE, GCSP, GCSP_HUMAN, GLDC, Glycine cleavage system P protein, glycine cleavage system protein P, Glycine decarboxylase, glycine decarboxylase P protein, Glycine dehydrogenase decarboxylating mitochondrial, Glycine dehydrogenase [decarboxylating], mitochondrial, Gycine dehydrogenase decarboxylating, HYGN1, MGC138198, MGC138200, NKH.

    Background: The glycine cleavage system is comprised of AMT (known as Protein T), GCSH (known as Protein H), DLD (known as Protein L) and GLDC (known as Protein P), all of which work together to catalyze the cleavage and degradation of glycine. GLDC (glycine dehydrogenase ), also known as GCE, GCSP (glycine cleavage system P protein) or HYGN1, is a 1,020 amino acid protein that localizes to the mitochondria and belongs to the gcvP family. GLDC binds to glycine and enables the methylamine group from glycine to be transferred to the Protein T. GLDC exists as a homodimer and utilizes pyridoxal phosphate as a cofactor. Mutations in the gene encoding GLDC leads to nonketotic hyperglycinemia (NKH), also known as glycine encephalopathy (GCE), an autosomal recessive disease characterized by accumulation of a large amount of glycine in body fluid and by severe neurological symptoms.

    基因ID
    2731
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