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NRN1 抗体 (Center)

NRN1 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500332
发货至: 中国
  • 抗原 See all NRN1 抗体
    NRN1 (Neuritin 1 (NRN1))
    抗原表位
    • 15
    • 5
    • 1
    • 1
    • 1
    • 1
    Center
    适用
    • 30
    • 17
    • 16
    人, 小鼠
    宿主
    • 29
    • 1
    克隆类型
    • 29
    • 1
    多克隆
    标记
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NRN1 antibody is un-conjugated
    应用范围
    • 20
    • 13
    • 13
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects Neuritin.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse
    纯化方法
    Peptide affinity chromatography
    免疫原
    Neuritin antibody was raised against a 20 amino acid peptide from near the center of human neuritin.
    亚型
    IgG
    Top Product
    Discover our top product NRN1 Primary Antibody
  • 应用备注
    ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    NRN1 (Neuritin 1 (NRN1))
    别名
    Neuritin (NRN1 产品)
    别名
    NRN antibody, dJ380B8.2 antibody, 0710008J23Rik antibody, Cpg15 antibody, Nrn antibody, neuritin antibody, nrn1 antibody, zgc:92828 antibody, NRN1 antibody, cpg15 antibody, nrn antibody, nrn1-a antibody, nrn1-b antibody, nrn1b antibody, neuritin 1 antibody, neuritin 1a antibody, neuritin 1 S homeolog antibody, neuritin 1 L homeolog antibody, NRN1 antibody, Nrn1 antibody, nrn1a antibody, nrn1 antibody, nrn1.S antibody, nrn1.L antibody
    背景
    As the nervous system of a complex organism develops, it establishes functional networks through the growth and retraction of synaptic connections from growing axons and dendrites. This synaptic remodeling involves neuro-transmitter signaling, activation of neurotrophin receptors and alterations in gene expression. One such gene whose expression is increased by neural activity is neuritin, a GPI-anchored protein that is expressed in postmitotic differentiating neurons of the developing nervous system. Its expression is also induced by the neurotrophins BDNF and NT-3. Purified recombinant neuritin promotes neurite outgrowth and arborization in primary embryonic neuronal cultures, suggesting that neuritin may play a role as a downstream effector of activity-induced neurite outgrowth. More recent experiments have shown that neuritin is required for the androgen-induced axonal elongation in motor neurons and is upregulated following spinal cord injury, suggesting that neuritin may also play a role in survival and axonal regeneration.Synonyms: NRN, NRN1
    基因ID
    51299
    NCBI登录号
    NP_057672
    UniProt
    Q9NPD7
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