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NANOS3 抗体 (C-Term)

NANOS3 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500324
发货至: 中国
  • 抗原 See all NANOS3 抗体
    NANOS3 (Nanos Homolog 3 (NANOS3))
    抗原表位
    • 15
    • 5
    • 1
    • 1
    C-Term
    适用
    人, 小鼠, 大鼠
    宿主
    • 24
    • 1
    克隆类型
    • 24
    • 1
    多克隆
    标记
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NANOS3 antibody is un-conjugated
    应用范围
    • 20
    • 13
    • 13
    • 12
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects Nanos3 at C-term. It will not cross-react with either Nanos 1 or Nanos2.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat
    纯化方法
    Peptide affinity chromatography
    免疫原
    Nanos3 antibody was raised against a 16 amino acid peptide near the carboxy terminus of the human Nanos3.
    亚型
    IgG
    Top Product
    Discover our top product NANOS3 Primary Antibody
  • 应用备注
    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    NANOS3 (Nanos Homolog 3 (NANOS3))
    别名
    NANOS3 (NANOS3 产品)
    别名
    NANOS1L antibody, NOS3 antibody, nos3 antibody, cb725 antibody, nanos antibody, nanos1 antibody, nos1 antibody, nanos C2HC-type zinc finger 3 antibody, nanos homolog 3 (Drosophila) antibody, nanos homolog 3 antibody, NANOS3 antibody, Nanos3 antibody, nanos3 antibody
    背景
    Nanos is a zinc-finger containing, RNA-binding protein that has been implicated in germ cell development in both invertebrates and vertebrates. In drosophila, Nanos represses apoptosis during development to ensure proper germ-line development. Unlike Nanos1 whose expression in mice is dispensable, the Nanos2 and Nanos3 proteins are required for germ cell development. Nanos2-null primordial germ cells (PGCs) die only in the male gonads and show no defects in females, while Nanos3-null PGCs are lost during the migration stage regardless of sex. Nanos2 and Nanos3 have distinct expression patterns during embryo development, suggesting that these two proteins do not have redundant functions. However, expression of Nanos2 can at least partially replace Nanos3 function in a Nanos3-null background. Nanos3 expression can not rescue Nanos2-null defects.Synonyms: MGC120114, NANOS1L, NOS3, Nanos homolog 3
    基因ID
    342977
    NCBI登录号
    NP_001092092
    UniProt
    Q495E5
    途径
    ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Response to Molecule of Bacterial Origin, Myometrial Relaxation and Contraction, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling
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