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FMN1 抗体 (AA 651-750) (AbBy Fluor® 750)

FMN1 适用: 人, 大鼠 WB, IF (p), IF (cc) 宿主: 兔 Polyclonal AbBy Fluor® 750
产品编号 ABIN5002769
发货至: 中国
  • 抗原 See all FMN1 抗体
    FMN1 (Formin 1 (FMN1))
    抗原表位
    • 14
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 651-750
    适用
    • 25
    • 15
    • 2
    人, 大鼠
    宿主
    • 23
    • 3
    克隆类型
    • 25
    • 1
    多克隆
    标记
    • 10
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FMN1 antibody is conjugated to AbBy Fluor® 750
    应用范围
    • 22
    • 12
    • 12
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    交叉反应
    人, 大鼠
    预测反应
    Mouse,Dog,Cow,Sheep
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human FMN1/Formin 1
    亚型
    IgG
    Top Product
    Discover our top product FMN1 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    FMN1 (Formin 1 (FMN1))
    别名
    FMN1/Formin 1 (FMN1 产品)
    别名
    si:dkey-81b15.10 antibody, fmn antibody, formin antibody, FMN antibody, LD antibody, BB164513 antibody, Fmn antibody, formin-1 antibody, ld antibody, RGD1306349 antibody, RGD1310100 antibody, formin 1 antibody, fmn1 antibody, FMN1 antibody, Fmn1 antibody
    背景

    Synonyms: FMN, Formin 1, Formin1, Formin-1, LD, Limb deformity protein homolog, FMN1_HUMAN.

    Background: The temporal genetic hierarchy influencing normal limb development can deregulate and mediate mammalian developmental syndromes. In mice, the limb deformity (ld) locus influences normal limb development and gives rise to alternative mRNAs that can translate into a family of proteins known as formins. Formins play a crucial role in cytoskeletal reorganization by influencing Actin filament assembly. Formins co-localize with the actin cytoskeleton and can translocate into the cell cytosol and into the nucleus in an HGF-dependent manner. Vertebrate nuclear formins can control polarizing activity in limb buds through establishment of a Sonic hedgehog/FGF-4 feedback loop. Deficiency mutations at the mammalian ld locus lead to profound developmental defects in limb and kidney formation. The human Formin 1 and 2 genes map to chromosome 15q13.3 and 1q43, respectively.

    基因ID
    342184
    途径
    Regulation of Actin Filament Polymerization
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