FMN1 抗体 (AA 651-750) (AbBy Fluor® 680)
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- 抗原 See all FMN1 抗体
- FMN1 (Formin 1 (FMN1))
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抗原表位
- AA 651-750
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FMN1 antibody is conjugated to AbBy Fluor® 680
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- 交叉反应
- 人, 大鼠
- 预测反应
- Mouse,Dog,Cow,Sheep
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human FMN1/Formin 1
- 亚型
- IgG
- Top Product
- Discover our top product FMN1 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- FMN1 (Formin 1 (FMN1))
- 别名
- FMN1/Formin 1 (FMN1 产品)
- 别名
- si:dkey-81b15.10 antibody, fmn antibody, formin antibody, FMN antibody, LD antibody, BB164513 antibody, Fmn antibody, formin-1 antibody, ld antibody, RGD1306349 antibody, RGD1310100 antibody, formin 1 antibody, fmn1 antibody, FMN1 antibody, Fmn1 antibody
- 背景
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Synonyms: FMN, Formin 1, Formin1, Formin-1, LD, Limb deformity protein homolog, FMN1_HUMAN.
Background: The temporal genetic hierarchy influencing normal limb development can deregulate and mediate mammalian developmental syndromes. In mice, the limb deformity (ld) locus influences normal limb development and gives rise to alternative mRNAs that can translate into a family of proteins known as formins. Formins play a crucial role in cytoskeletal reorganization by influencing Actin filament assembly. Formins co-localize with the actin cytoskeleton and can translocate into the cell cytosol and into the nucleus in an HGF-dependent manner. Vertebrate nuclear formins can control polarizing activity in limb buds through establishment of a Sonic hedgehog/FGF-4 feedback loop. Deficiency mutations at the mammalian ld locus lead to profound developmental defects in limb and kidney formation. The human Formin 1 and 2 genes map to chromosome 15q13.3 and 1q43, respectively.
- 基因ID
- 342184
- 途径
- Regulation of Actin Filament Polymerization
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