MED4 抗体 (C-Term)
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- 抗原 See all MED4 抗体
- MED4 (Mediator Complex Subunit 4 (MED4))
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抗原表位
- C-Term
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MED4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects MED4. It only recognizes the largest isoform.
- 交叉反应 (详细)
- Species reactivity (tested):Human, mouse, rat
- 纯化方法
- Peptide affinity chromatography
- 免疫原
- MED4 antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human MED4.
- 亚型
- IgG
- Top Product
- Discover our top product MED4 Primary Antibody
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- 应用备注
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ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- 抗原
- MED4 (Mediator Complex Subunit 4 (MED4))
- 别名
- MED4 (MED4 产品)
- 别名
- zgc:110646 antibody, ARC36 antibody, DRIP36 antibody, HSPC126 antibody, TRAP36 antibody, VDRIP antibody, Vdrip antibody, 2410046H15Rik antibody, Vdirp antibody, mediator complex subunit 4 antibody, mediator complex subunit 4 S homeolog antibody, med4 antibody, med4.S antibody, MED4 antibody, Med4 antibody
- 背景
- The mediator complex is a multi-protein transcriptional co-activator that is expressed ubiquitously in eukaryotes from yeast to mammals and is required for induction of RNA polymerase II (pol II) transcription by DNA binding transcription factor. One of the proteins in this complex is MED4. This protein has also been shown to be part of the vitamin D receptor interacting complex. MED4 was recently identified as an HIV dependency factor (HDF), suggesting that MED4 may be an important drug target in HIV treatment. At least three isoforms of MED4 are known to exist.Synonyms: ARC36, Activator-recruited cofactor 36 kDa component, DRIP36, HSPC126, Mediator complex 4, Mediator of RNA polymerase II transcription subunit 4, TRAP/SMCC/PC2 subunit p36 subunit, VDRIP, Vitamin D3 receptor-interacting protein complex 36 kDa component
- 基因ID
- 29079
- NCBI登录号
- NP_054885
- UniProt
- Q9NPJ6
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Regulation of Lipid Metabolism by PPARalpha
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