FIG4 抗体 (AA 1-100) (AbBy Fluor® 750)
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- 抗原 See all FIG4 抗体
- FIG4 (FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4))
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抗原表位
- AA 1-100
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FIG4 antibody is conjugated to AbBy Fluor® 750
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 大鼠
- 预测反应
- Human,Mouse,Dog,Sheep,Pig,Chicken,Monkey
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human FIG4
- 亚型
- IgG
- Top Product
- Discover our top product FIG4 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- FIG4 (FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4))
- 别名
- FIG4/SAC3 (FIG4 产品)
- 别名
- A530089I17Rik antibody, AI326867 antibody, Sac3 antibody, ALS11 antibody, CMT4J antibody, KIAA0274 antibody, SAC3 antibody, YVS antibody, dJ249I4.1 antibody, Kiaa0274 antibody, RGD1311375 antibody, FIG4 phosphoinositide 5-phosphatase antibody, Fig4 antibody, FIG4 antibody
- 背景
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Synonyms: 5-bisphosphate 5-phosphatase, Fig4, FIG4_HUMAN, KIAA0274, ALS11, Phosphatidylinositol 3, hSac3, Phosphatidylinositol 3,5 bisphosphate 5 phosphatase, Polyphosphoinositide phosphatase, SAC domain containing protein 3, SAC domain-containing protein 3, SAC3.
Background: FIG4 is a 907 amino acid protein that contains one SAC domain through which it is thought to function as a phosphoinositide phosphatase that may play an important role in signal transduction and vesicle trafficking. Defects in the gene encoding FIG4 are the cause of Charcot-Marie-Tooth disease type 4J (CMT4J) and amyotrophic lateral sclerosis type 11 (ALS11), both of which negatively affect the nervous system. CMT4J is a recessive demyelinating disorder of the peripheral nervous system and is characterized by reduced motor nerve conduction velocities and axonal degeneration. Unlike CMT4J, ALS11 is characterized by the degeneration of upper motor neurons in the brain and lower neurons in the spinal cord, causing paralysis and, ultimately, death.
- 途径
- Inositol Metabolic Process
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