Fibrillin 2 抗体 (AA 1001-1200) (AbBy Fluor® 750)
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- 抗原 See all Fibrillin 2 (FBN2) 抗体
- Fibrillin 2 (FBN2)
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抗原表位
- AA 1001-1200
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Fibrillin 2 antibody is conjugated to AbBy Fluor® 750
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Fibrillin 2
- 亚型
- IgG
- Top Product
- Discover our top product FBN2 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- Fibrillin 2 (FBN2)
- 别名
- Fibrillin 2 (FBN2 产品)
- 别名
- CCA antibody, DA9 antibody, BC063774 antibody, Fib-2 antibody, mKIAA4226 antibody, sne antibody, sy antibody, FBN2 antibody, fibrillin 2 antibody, fibrillin 3 antibody, FBN2 antibody, Fbn2 antibody, FBN3 antibody
- 背景
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Synonyms: CCA, congenital contractural arachnodactyly Marfanoid-like, DA9, FBN2, FBN2_HUMAN, fibrillin 2 congenital contractural arachnodactyly, Fibrillin-2.
Background: Extracellular glycoproteins fibrillin-1 and -2 are major components of connective tissue microfibrils. Fibrillin-2 containing microfibrils regulate the early process of elastic fiber assembly in tissue. Mutations in the fibrillin-2 gene resulting in impaired assembly of fibrillin-2 may lead to molecular congenital contractural arachnodactyly. Fibrillin-2 constitutes the backbone of microfibrils which insert directly into the lamina densa of basement membranes. Epithelial cells primarily deposit fibrillin into the extracellular matrix in a nonfibrillar form. Mutations in the 8-cysteine motif of Fibrillin-2 alters its binding to microfibril-associated glycoprotein-1 (MAGP-1), which may increase the severity of congenital contractural arachnodactyly.
- 途径
- Maintenance of Protein Location, SARS-CoV-2 Protein Interactome
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