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LY96 抗体 (Center)

This anti-LY96 antibody is a 兔 多克隆 antibody detecting LY96 in WB, IF, IHC (p) 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN500262
发货至: 中国

Quick Overview for LY96 抗体 (Center) (ABIN500262)

抗原

See all LY96 抗体
LY96 (Lymphocyte Antigen 96 (LY96))

适用

  • 48
  • 13
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 40
  • 14

克隆类型

  • 43
  • 11
多克隆

标记

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  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This LY96 antibody is un-conjugated

应用范围

  • 40
  • 16
  • 14
  • 10
  • 6
  • 6
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 8
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Center

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Ion exchange chromatography

    免疫原

    MD-2 antibody was raised against a peptide corresponding to amino acids near the middle region of human MD-2.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 0.5 to 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    LY96 (Lymphocyte Antigen 96 (LY96))

    别名

    MD-2

    背景

    MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs) (1-3). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses (4). TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS (5,6). The specificity of this response is determined by the species of MD-2, e.g., human MD-2 can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4 (7).Synonyms: ESOP-1, ESOP1, LY96, Lymphocyte antigen 96, MD2

    NCBI登录号

    NP_056179

    UniProt

    Q9Y6Y9

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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