EN2 抗体 (AA 281-333) (AbBy Fluor® 750)
-
- 抗原 See all EN2 抗体
- EN2 (Engrailed Homeobox 2 (EN2))
-
抗原表位
- AA 281-333
-
适用
- 人, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This EN2 antibody is conjugated to AbBy Fluor® 750
-
应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠
- 预测反应
- Rat,Dog,Sheep,Pig
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human EN2/Engrailed 2
- 亚型
- IgG
- Top Product
- Discover our top product EN2 Primary Antibody
-
-
- 应用备注
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
-
- 抗原
- EN2 (Engrailed Homeobox 2 (EN2))
- 别名
- EN2/Engrailed 2 (EN2 产品)
- 别名
- EN2 antibody, en antibody, en2 antibody, BB131122 antibody, En-2 antibody, RGD1561842 antibody, Gg-En-2 antibody, engrailed homeobox 2 antibody, engrailed homeobox antibody, engrailed 2 antibody, EN2 antibody, en antibody, En2 antibody
- 背景
-
Synonyms: Homeobox protein engrailed-2, Homeobox protein en-2, Hu-En-2, EN2
Background: The engrailed-2 gene, EN2, a murine homolog of the Drosophila homeobox gene engrailed (EN), is required for midbrain and cerebellum development and dorsal/ventral patterning of the limbs as well as apical ectodermal ridge formation. In Drosophila, the EN gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Human EN-1 and EN-2 are homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. Different mutations in the mouse homologs, EN-1 and EN-2, produce different developmental defects that frequently are lethal. EN-1 is highly expressed by essentially all dopaminergic neurons in the substantia nigra and ventral tegmentum. EN-1 and EN-2 regulate expression of a-synuclein, a gene that is genetically linked to Parkinson?s disease. During early brain development mouse EN-2 is expressed in a broad band across most of the mid-hindbrain region. EN-2 is also expressed in mouse myoblasts and has been assiciated with cerebellar hypoplasia.
- 基因ID
- 2020
- UniProt
- P19622
-