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BIRC7 抗体 (AA 264-280)

Name: BIRC7 抗体 (AA 264-280)
SKU: ABIN500182
Availability: OutOfStock

BIRC7 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

Western blot analysis of Livin expression in human Raji cell lysate with this product at 0. (BIRC7 抗体 (AA 264-280))

Immunohistochemistry of Livin in human small intestine tissue with this product at 5 μg/ml. (BIRC7 抗体 (AA 264-280))

IHC (p)

2 images

产品编号 ABIN500182

发货至: 中国

Datasheet as PDF

抗原 See all BIRC7 抗体

BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))
抗原表位
15

8

7

5

3

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 264-280
适用
63

15

15

2

2

2

1
人
宿主
55

7

1
兔
Compatible Secondaries
克隆类型
56

7
多克隆
标记
33

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This BIRC7 antibody is un-conjugated
应用范围
50

20

16

13

13

12

10

6

6

3

2

2

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

特异性

This antibody detects BIRC7 / LIVIN.

交叉反应（详细）

Species reactivity (tested):Human

纯化方法

Peptide affinity chromatography

免疫原

Livin antibody was raised with a synthetic peptide corresponding to amino acids 264 to 280 of the short form and 281 to 298 of the long form of human Livin (1,3). .Remarks: The sequence is identical between a and b forms of the Livin proteins.

亚型

IgG

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应用备注

ELISA. Western blot: 2 to 4 μg/mL. Human Raji cell lysate can be used as a positive control and aband at 33 kDa can be detected. A lower but much weaker band at 30 kDa was detected inRaji cell lysate, which may represent the short form of Livin. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
缓冲液

PBS containing 0.02 % sodium azide

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
抗原

BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

别名

BIRC7 / LIVIN (BIRC7 产品)

别名

KIAP antibody, LIVIN antibody, ML-IAP antibody, MLIAP antibody, RNF50 antibody, EIAP/XLX antibody, XLX antibody, kiap antibody, livin antibody, ml-iap antibody, mliap antibody, rnf50 antibody, xEIAP antibody, RGD1562883 antibody, zgc:165605 antibody, E130019N06 antibody, Livin antibody, birc7 antibody, bird7a antibody, xEIAP/XLX antibody, xlx antibody, EIAP/XLX-B antibody, birc7b antibody, baculoviral IAP repeat containing 7 antibody, baculoviral IAP repeat-containing 7 antibody, baculoviral IAP repeat-containing 7 (livin) antibody, baculoviral IAP repeat containing 7 S homeolog antibody, baculoviral IAP repeat containing 7 L homeolog antibody, BIRC7 antibody, birc7 antibody, Birc7 antibody, birc7.S antibody, birc7.L antibody

背景

Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. A novel member in the IAP protein family was recently identified and designated Livin and KIAP for kidney IAP (1,2). Livin/XIAP contains a single baculoviral IAP repeat (BIR) domain and a RING finger domain and has two isoforms termed Livin-a and Livin-b (1,3). Transfection of Livin in cells resulted in protection from apoptosis induced by FADD, BAX, RIP, RIP3 and DR6 (1). Livin has direct interaction with several caspases including caspase-3, -7, and -9. Livin inhibits the activation of caspase-9 induced by Apaf-1, cytochrome c, and dATP. The two isoforms of Livin appear to have different functions and tissue distributions.Synonyms: Baculoviral IAP repeat-containing protein 7, KIAP, Kidney inhibitor of apoptosis protein, Livin, MLIAP, Melanoma inhibitor of apoptosis protein, RING finger protein 50, RNF50

基因ID

79444

NCBI登录号

NP_071444

UniProt

Q96CA5